850149P

18:1 PI

Avanti Polar Lipids

• Synonym(s): 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoinositol (ammonium salt); DOPI; PI(18:1(9Z)/18:1(9Z)); 110659
• Empirical Formula (Hill Notation): C₄₅H₈₆NO₁₃P
• CAS Number: 799268-53-4
• Molecular Weight: 880.14
• UNSPSC Code: 51191904
• NACRES: NA.25

Properties

• description: 1,2-dioleoyl-sn-glycero-3-phospho-(1′-myo-inositol) (ammonium salt)
• Assay: >99% (TLC)
• form: powder
• packaging: pkg of 1 × 100 μg (with stopper and crimp cap (850149P-100ug)); pkg of 1 × 500 μg (with stopper and crimp cap (850149P-500ug))
• manufacturer/tradename: Avanti Polar Lipids
• lipid type: phospholipids; cardiolipins
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: [H][C@@](COP([O-])(O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](O)[C@H]1O)=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O.[NH4+]

Description

General description

Inositol phospholipid species are membrane-bound signaling molecules that have been implicated in almost all aspects of cellular physiology, including cellular growth, metabolism, proliferation, and survival.

Phosphatidylinositol (PI) is a phospholipid which accounts for 10% of the lipid in the cells of eukaryotes. 18:1 PI (1,2-dioleoyl-sn-glycero-3-phospho-(1′-myo-inositol)/ DOPI) is an anionic phospholipid.

Application

18:1 PI (1,2-dioleoyl-sn-glycero-3-phospho-(1′-myo-inositol)/ DOPI) has been used to prepare lipid mix giant unilamellar vesicles (LM-GUVs).

Biochem/physiol Actions

Phosphatidylinositol (PI) can serve as a precursor for inositol phosphates, that are soluble in water. 18:1 PI (1,2-dioleoyl-sn-glycero-3-phospho-(1′-myo-inositol)/ DOPI) may serve as a substrate for lysosomal phospholipase A2 (LPLA2) and can promote LPLA2 activity.

Packaging

2 mL Amber Serum Vial with Stopper and Crimp Cap (850149P-100ug)

2 mL Amber Serum Vial with Stopper and Crimp Cap (850149P-500ug)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Safety Information

• Storage Class Code: 11 - Combustible Solids