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92260

Sigma-Aldrich

Trimethylamine solution

31-35 wt. % in ethanol, 4.2 M, contains toluene as stabilizer

Synonym(s):

N,N,N-Trimethylamine, N,N-Dimethylmethanamine, TMA solution

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About This Item

Linear Formula:
(CH3)3N
CAS Number:
75-50-3
Molecular Weight:
59.11
Beilstein:
956566
MDL number:
MFCD00008327
UNSPSC Code:
12352100
PubChem Substance ID:
57653373
NACRES:
NA.22

form

liquid

Quality Level

200

contains

toluene as stabilizer

concentration

31-35 wt. % in ethanol
4.2 M

SMILES string

CN(C)C

InChI

1S/C3H9N/c1-4(2)3/h1-3H3

InChI key

GETQZCLCWQTVFV-UHFFFAOYSA-N

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Application

Trimethylamine ethanolic solution is used in the preparation of:
  • Glycidyltrimethylammonium bromide.
  • Trimethylammonium salt of ethylenediaminetetraacetic acid (EDTA).
  • Quaternized ammonium chlorides that exhibit antimicrobial activity.

Signal Word

Danger

Hazard Statements

H224,H314,H335

Hazard Classifications

Eye Dam. 1 - Flam. Liq. 1 - Skin Corr. 1B - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

-4.0 °F - closed cup

Flash Point(C)

-20 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Glycidyltrimethylammonium chloride and related compounds.
McClure JD.
The Journal of Organic Chemistry, 35(6), 2059-2061 (1970)
Demineralization in organic solvents by alkylammonium salts of ethylenediaminetetra-acetic acid.
Scott JE and Kyffin TW
The Biochemical Journal, 169(3), 697-701 (1978)
Preparation and antimicrobial behaviour of quaternary ammonium thiol derivatives able to be grafted on metal surfaces.
Thebault P, et al.
European Journal of Medicinal Chemistry, 44(2), 717-724 (2009)
E L Barrett et al.
Annual review of microbiology, 39, 131-149 (1985-01-01)
Trimethylamine oxide, which is found in relatively high concentrations in the tissues of marine animals, serves as an electron acceptor in the anaerobic metabolism of a number of bacteria associated primarily with three environments: the marine environment (e.g. Alteromonas and
M Al-Waiz et al.
Clinical pharmacology and therapeutics, 42(5), 588-594 (1987-11-01)
Trimethylamine (TMA) and its N-oxide (TMAO) are normal components of human urine. They are present in the diet and also derived from the enterobacterial metabolism of precursors such as choline. Dietary TMA is almost entirely metabolized to and excreted as
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