Skip to Content
Merck
All Photos(1)

Documents

764620

Sigma-Aldrich

Poly(D,L-lactide)

average Mn 10,000, PDI ≤1.2

Synonym(s):

PDLA, PLA, polyDL-lactide

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

UNSPSC Code:
12162002
NACRES:
NA.23

form

solid

optical activity

[α]/D 0°, c = 0.5% in chloroform

mol wt

average Mn 10,000

degradation timeframe

<6 months

mp

287-293 °C

PDI

≤1.2

storage temp.

2-8°C

Looking for similar products? Visit Product Comparison Guide

Application

Used in Drug Delivery including coating nanoparticles1. Can be end-group functionalizated2 or used as a macroinitiator/block precursor3.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Wolf, Florian F.; et al.
Macromolecules, 42, 5622-5628 (2009)
Zhang, Wen-Bin; et al.
Macromolecules, 44, 2589-2596 (2011)
Preparation of Protein-Loaded Poly(L-Lactide) Microspheres by Solution-Enhanced Dispersion by Supercritical CO2
Chen A Z, et al.
Journal of Biomimetics, Biomaterials, and Tissue Engineering, 11, 93-100 (2011)

Articles

Poly(Glycerol Sebacate) in Tissue Engineering and Regenerative Medicine

The world of commercial biomaterials has stagnated over the past 30 years as few materials have successfully transitioned from the bench to clinical use. Synthetic aliphatic polyesters have continued to dominate the field of resorbable biomaterials due to their long history and track record of approval with the U.S. Food and Drug Administration (FDA).

Electrospun Nanofibers for Drug Delivery Systems

Local delivery of bioactive molecules using an implantable device can decrease the amount of drug dose required as well as non-target site toxicities compared to oral or systemic drug administration.

Fabrication of Drug-loaded Microparticles Using Hydrogel Technology and Recent Innovation in Automation

Microparticle drug delivery systems have been extensively researched and applied to a wide variety of pharmaceutical and medical applications due to a number of advantages including injectability, local applicability to target tissues and sites, and controlled drug delivery over a given time period.

Biodegradable Polyester Based Nanoparticle Formation by Miniemulsion Technique

Aliphatic polyesters such as polylactide, poly(lactide-co-glycolide) and polycaprolactone, as well as their copolymers, represent a diverse family of synthetic biodegradable polymers that have been widely explored for medical uses and are commercially available.

See All

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service