709700

2-(Boc-amino)benzylamine

• Synonym(s): (2-Aminomethyl-phenyl)-carbamic acid tert-butyl ester, tert-Butyl N-(2-aminomethylphenyl)carbamate
• Empirical Formula (Hill Notation): C₁₂H₁₈N₂O₂
• CAS Number: 849020-94-6
• Molecular Weight: 222.28
• MDL number: MFCD04037902
• UNSPSC Code: 12352100
• PubChem Substance ID: 329762890
• NACRES: NA.22

Properties

• form: liquid
• Quality Level: 100
• bp: 238-242 °C
• density: 1.054 g/mL at 25 °C
• functional group: amine
• SMILES string: CC(C)(C)OC(=O)Nc1ccccc1CN
• InChI: 1S/C12H18N2O2/c1-12(2,3)16-11(15)14-10-7-5-4-6-9(10)8-13/h4-7H,8,13H2,1-3H3,(H,14,15)
• InChI key: BFFRNSYPZZUZDR-UHFFFAOYSA-N

Description

Application

Reactant for:

• Two-step syntheses of fused quinoxaline-benzodiazepines and bis-benzodiazepines employing a double UDC (Ugi/Deprotect/Cyclize) strategy
• Preparation of hydroquinazoline scaffolds via microwave-promoted Ugi reaction and cyclization
• Preparation of pyrazinone inhibitors of mast cell tryptase

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H302,H317
• Precautionary Statements: P261 - P264 - P272 - P280 - P301 + P312 - P302 + P352
• Hazard Classifications: Acute Tox. 4 Oral - Skin Sens. 1
• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point(F): 161.1 °F - closed cup
• Flash Point(C): 71.7 °C - closed cup