248509

(S)-(−)-N-(Trifluoroacetyl)pyrrolidine-2-carbonyl chloride solution

0.1 M in methylene chloride

• Synonym(s): (S)-(−)-N-(Trifluoroacetyl)prolyl chloride solution, TPC
• Empirical Formula (Hill Notation): C₇H₇ClF₃NO₂
• CAS Number: 36724-68-2
• Molecular Weight: 229.58
• Beilstein: 480791
• MDL number: MFCD00010418
• UNSPSC Code: 12352005
• PubChem Substance ID: 24854932
• NACRES: NA.22

Properties

• optical purity: ee: 95% (GLC)
• concentration: 0.1 M in methylene chloride
• refractive index: n20/D 1.424
• density: 1.308 g/mL at 25 °C
• storage temp.: 2-8°C
• SMILES string: FC(F)(F)C(=O)N1CCC[C@H]1C(Cl)=O
• InChI: 1S/C7H7ClF3NO2/c8-5(13)4-2-1-3-12(4)6(14)7(9,10)11/h4H,1-3H2/t4-/m0/s1
• InChI key: NUOYJPPISCCYDH-BYPYZUCNSA-N

Description

Application

(S)-(−)-N-(Trifluoroacetyl)pyrrolidine-2-carbonyl chloride can be used as a chiral derivatization reagent:

• In the chiral separation of psychoactive, cathinone- and amphetamine-related drugs using GC-MS technique.
• In the estimation of cathinone related drug enantiomers in biological samples like urine and plasma using GC-MS technique.

Safety Information

• Pictograms: GHS08,GHS07
• Signal Word: Warning
• Hazard Statements: H315,H319,H336,H351
• Precautionary Statements: P202 - P261 - P264 - P302 + P352 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Carc. 2 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Central nervous system
• Storage Class Code: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves