TDO2
tryptophan 2,3-dioxygenase
Synonyms:
TDO, TO, TPH2, TRPO
Species:
Human TDO2 (6999), Mouse Tdo2 (56720), Rat Tdo2 (64206), cow TDO2 (530397), sheep TDO2 (101109739), domestic guinea pig Tdo2 (100727713), naked mole-rat Tdo2 (101711781), Domestic Rabbit TDO2 (100344083), chicken TDO2 (422409), dog TDO2 (475476) ...More
UniProtKB ID:
Gene ID:
- Human(6999) Summary: This gene encodes a heme enzyme that plays a critical role in tryptophan metabolism by catalyzing the first and rate-limiting step of the kynurenine pathway. Increased activity of the encoded protein and subsequent kynurenine production may also play a role in cancer through the suppression of antitumor immune responses, and single nucleotide polymorphisms in this gene may be associated with autism. [provided by RefSeq, Feb 2012]
- Mouse(56720) tryptophan 2,3-dioxygenase
- Rat(64206) tryptophan 2,3-dioxygenase
- cow(530397) tryptophan 2,3-dioxygenase
- sheep(101109739) tryptophan 2,3-dioxygenase
- domestic guinea pig(100727713) tryptophan 2,3-dioxygenase
- naked mole-rat(101711781) tryptophan 2,3-dioxygenase
- Domestic Rabbit(100344083) tryptophan 2,3-dioxygenase
- chicken(422409) tryptophan 2,3-dioxygenase
- dog(475476) tryptophan 2,3-dioxygenase
- Horse(100069524) tryptophan 2,3-dioxygenase
- domestic cat(101090935) tryptophan 2,3-dioxygenase
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-TDO2, affinity isolated antibody,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot
Anti-TDO2, (N-terminal) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, guinea pig, human, mouse, rabbit, rat
Application
western blot
Anti-TDO2 Antibody, clone 7A6.1, clone 7A6.1, from mouse,
Species Reactivity
human, mouse
Application
immunohistochemistry
western blot
western blot
Anti-TDO2 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Small Molecule - Precursor
Product Number
Description
Species
Proteins
esiRNA
Product Number
Description
Species