1179333

Dexmedetomidine hydrochloride

United States Pharmacopeia (USP) Reference Standard

• Synonym(s): (+)-Medetomidine hydrochloride, (S)-Medetomidine hydrochloride, 4-[(S)-α,2,3-Trimethylbenzyl]imidazole monohydrochloride, 5-[(1S)-1-(2,3-Dimethylphenyl)ethyl]-1H-imidazole hydrochloride
• Empirical Formula (Hill Notation): C₁₃H₁₆N₂ · HCl
• CAS Number: 145108-58-3
• Molecular Weight: 236.74
• UNSPSC Code: 41116107
• NACRES: NA.24

Properties

• grade: pharmaceutical primary standard
• API family: dexmedetomidine, medetomidine
• manufacturer/tradename: USP
• application(s): pharmaceutical (small molecule)
• format: neat
• InChI: 1S/C13H16N2.ClH/c1-9-5-4-6-12(10(9)2)11(3)13-7-14-8-15-13;/h4-8,11H,1-3H3,(H,14,15);1H/t11-;/m0./s1
• InChI key: VPNGEIHDPSLNMU-MERQFXBCSA-N

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Dexmedetomidine hydrochloride USP reference standard for specified quality tests and assays.

Also used to prepare standard, system suitability, and sensitivity solution for assay and impurity analysis using liquid chromatography method and UV detector according to the given below monographs of United States Pharmacopeia (USP):

• Dexmedetomidine Injection
• Dexmedetomidine Hydrochloride

Biochem/physiol Actions

Dexmedetomidine hydrochloride is a highly potent and selective α2-adrenergic agonist with analgesic and sedative properties, the (+)-isomer of medetomidine. Dexmedetomidine hydrochloride is used clinically as an anesthetic agent to reduce anxiety and tension and promote relaxation and sedation without causing respiratory depression.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Safety Information

• Pictograms: GHS07,GHS09
• Signal Word: Warning
• Hazard Statements: H302 - H336 - H411
• Precautionary Statements: P261 - P264 - P271 - P273 - P301 + P312 - P304 + P340 + P312
• Hazard Classifications: Acute Tox. 4 Oral - Aquatic Chronic 2 - STOT SE 3
• Target Organs: Central nervous system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable