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Astec® CYCLOBOND II Chiral (5 μm) HPLC Columns

L × I.D. 25 cm × 4.6 mm, HPLC Column

Synonym(s):

Cyclodextrin-Based Chiral Column

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About This Item

UNSPSC Code:
41115700
eCl@ss:
32110501
NACRES:
SB.52

product name

Astec® CYCLOBOND II Chiral HPLC Column, 5 μm particle size, L × I.D. 25 cm × 4.6 mm

material

stainless steel column

product line

Astec®

packaging

pkg of 1 ea

manufacturer/tradename

Astec®

parameter

0-50 °C temperature
172 bar pressure (2500 psi)

technique(s)

HPLC: suitable
LC/MS: suitable

L × I.D.

25 cm × 4.6 mm

matrix

silica particle platform
fully porous particle

matrix active group

cyclodextrin, gamma- phase

particle size

5 μm

pore size

100 Å

operating pH

3.5-7

separation technique

chiral

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General description

Consisting of eight glucopyranose units arranged in a truncated cone shape, CYCLOBOND II is an excellent chiral selector for multi-ring structures. It is useful for isomeric compounds based on anthracene, chrysene and pyrene type ring structures. CYCLOBOND II offers good selectivity and stability and is applicable to the polar organic mode of separation. Applications include steroids, porphyrins, FMOC amino acids.

  • Bonded phase: Underivatized, native γ-cyclodextrin

Resources:
CYCLOBOND FAQs
CYCLOBOND Reference Bibliography
Chiral Product Literature

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Legal Information

Astec is a registered trademark of Merck KGaA, Darmstadt, Germany

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Certificates of Analysis (COA)

Lot/Batch Number
279465-01
279463-01
279436-01
279435-01
279404-01

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Series of homologous displacers for preparative chiral displacement chromatographic separations on Cyclobond-II columns
Quintero,Gilberto, et al.
Journal of Chromatography A, 693 (1), 1-5 (1995)
Separation and identification of sulfurized alkylphenols in oil by high-performance liquid chromatography with evaporative light scattering and mass spectrometric detection
Chen, Evan N., Jr., Nero, Vincent P.
Journal of Chromatography A, 549, 247-256 (1991)
A M Abushoffa et al.
Journal of chromatography. A, 700(1-2), 51-58 (1995-05-12)
The methods of separation of the enantiomers of the chiral drug oxamniquine are compared, between HPLC with either cyclodextrins and their related derivatives as chiral selectors in the mobile phase or immobilised in a chiral stationary phase (as Cyclobond I
Optical resolution of flavanones by high-performance liquid chromatography on various chiral stationary phases
Krause, Martin; Galensa, Rodolf
Journal of Chromatography A, 514, 147-159 (1990)
Yasith S Nanayakkara et al.
Journal of chromatography. A, 1305, 94-101 (2013-08-03)
Isochromene derivatives are very important precursors in the natural products industry. Hence the enantiomeric separations of chiral isochromenes are important in the pharmaceutical industry and for organic asymmetric synthesis. Here we report enantiomeric separations of 21 different chiral isochromene derivatives
View All Related Papers

Related Content

Astec CYCLOBOND™

CYCLOBOND is the name given to Astec technology for bonding cyclodextrins to a high purity silica gel through a stable ether linkage.

Chromatograms

application for HPLC

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