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SAB4700559

Sigma-Aldrich

Monoclonal Anti-Cd80 antibody produced in hamster

clone 16-10A1, purified immunoglobulin, buffered aqueous solution

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

hamster

Quality Level

100

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

16-10A1, monoclonal

form

buffered aqueous solution

species reactivity

mouse, canine

concentration

1 mg/mL

technique(s)

flow cytometry: suitable

isotype

IgG2

NCBI accession no.

NM_009855.2

UniProt accession no.

Q00609

shipped in

wet ice

storage temp.

2-8°C

target post-translational modification

unmodified

Gene Information

mouse ... Cd80(12519)

General description

The hamster monoclonal antibody 16-10A1 reacts with CD80 (B7-1), a 60 kDa single chain type I glycoprotein of immunoglobulin supergene family, expressed on professional antigen-presenting cells, such as dendritic cells, macrophages or activated B lymphocytes.

Immunogen

CD80-transfected CHO cell line

Application

The reagent is designed for Flow Cytometry analysis. Suggested working dilution is 6 μg/mL of sample. Indicated dilution is recommended starting point for use of this product. Working concentrations should be determined by the investigator.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Solution in phosphate buffered saline, pH 7.4, with 15 mM sodium azide.

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Storage Class Code

10 - Combustible liquids

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

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Sambuddho Mukherjee et al.
Journal of leukocyte biology, 80(1), 66-74 (2006-04-21)
Cytotoxic T-lymphocyte antigen 4 (CTLA4) is a well-studied T cell costimulatory receptor that is known to inhibit T cell activation. In this study, the relationship between strength of the first signal and costimulatory interactions on primary mouse CD4(+) T cells

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