SAB4200718

Anti-Elastin antibody, Mouse monoclonal

clone BA-4, purified from hybridoma cell culture

• Synonym(s): Anti-ELN, Anti-Tropoelastin
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: mouse
• antibody form: purified from hybridoma cell culture
• antibody product type: primary antibodies
• clone: BA-4, monoclonal
• form: buffered aqueous solution
• species reactivity: sheep, hamster, bovine, goat, frog, rabbit, porcine, human, guinea pig, canine
• concentration: ~1.0 mg/mL
• technique(s): immunoblotting: suitable; immunohistochemistry: 10-20 μg/mL using enzyme-retrieved formalin-fixed, paraffin-embedded sheep arterial tissue sections; immunoprecipitation (IP): suitable
• isotype: IgG1
• UniProt accession no.: P15502
• shipped in: dry ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... EMILIN3(2006)

Description

General description

Anti-Elastin antibody, Mouse monoclonal (mouse IgG1 isotype) is derived from the BA-4 hybridoma produced by the fusion of mouse myeloma cells and splenocytes from a BALB/c mouse immunized with bovine alpha-Elastin.

Immunogen

bovine alpha-Elastin

Application

Anti-Elastin antibody, Mouse monoclonal has been used in:

• immunohistochemistry
• immunoblot
• immunoprecipitation

Biochem/physiol Actions

Elastin (ELN) provides elasticity and is integrated with other proteins from the ECM in elastic fibrils. Elastin undergoes changes of morphology with aging and at many disease states. In addition, several heritable diseases, such as supravalvular aortic stenosis, cutis laxa, Marfan syndrome, pseudoxanthoma elasticum and Buschke-Ollendorf syndrome, may result from molecular defects of elastin.

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable