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P0930

Sigma-Aldrich

Polyvinylpyrrolidone

powder, BioXtra, suitable for mouse embryo cell culture

Synonym(s):

PVP, Polyvidone, Povidone

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About This Item

Linear Formula:
(C6H9NO)n
CAS Number:
9003-39-8
MDL number:
MFCD00149016
UNSPSC Code:
12352207
PubChem Substance ID:
24898139
NACRES:
NA.75

product line

BioXtra

form

powder

technique(s)

cell culture | embryo: suitable

viscosity number

28-32(lit.)

solubility

H2O: 100 mg/mL

application(s)

agriculture

SMILES string

C=CN1CCCC1=O

InChI

1S/C6H9NO/c1-2-7-5-3-4-6(7)8/h2H,1,3-5H2

InChI key

WHNWPMSKXPGLAX-UHFFFAOYSA-N

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General description

Polyvinylpyrrolidone (PVP)/polyvidone is used in cosmetics, medical and hair care products. Povidone iodine, a compound of polyvinylpyrrolidone and iodine can be used as an antiseptic and antibacterial agent. Dry form of PVP is available as a light flaky hygroscopic powder, which can absorb up to 40% of water by its weight.

Application

Polyvinylpyrrolidone has been used as a component in phosphate buffer saline (PBS) for immunostaining. It has also been used as a component in phosphate buffer saline (PBS) to wash parthenogenetic embryos for immunocytochemical analysis.

Other Notes

Polyvinylpyrrolidone is a component of Denhardt′s Solution and is included at a concentration of 1% (w/v) in the standard 50X stock solution.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Antiseptic drugs and disinfectants
Side Effects of Drugs Annual: A world-wide yearly survey of new data and trends in adverse drug reactions., 28, 261-261 (2005)
Suppression of Erk signalling promotes ground state pluripotency in the mouse embryo
Nichols J, et al.
Development, 136(19), 3215-3222 (2009)
Polymer synthesis and processing
Natural and Synthetic Biomedical Polymers, 1-31 (2014)
Cloned ferrets produced by somatic cell nuclear transfer
Li Z, et al.
Developmental Biology, 293, 439-448 (2006)
Bryan D James et al.
ACS biomaterials science & engineering, 6(6), 3673-3689 (2020-07-25)
Increasingly being recognized is the role of the complex microenvironment to regulate cell phenotype; however, the cell culture systems used to study these effects in vitro are lagging. The complex microenvironment is host to a combination of biological interactions, chemical
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