H2414

Anti-Humanin (HN) antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

• Synonym(s): Humanin Detection Antibody, Rabbit Anti-Humanin
• MDL number: MFCD05665229
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• Quality Level: 200
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• species reactivity: human
• technique(s): western blot: 1:500
• shipped in: dry ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... MT-RNR2(4550)

Description

General description

Humanin (HN) is a small polypeptide, derived from mitochondria. This protein is secreted by various cells and is localized in the plasma and bound to the cell membranes.

Immunogen

peptide corresponding to the humanin protein (amino acids 9-24).

Application

Anti-Humanin (HN) antibody produced in rabbit has been used in:

• immunohistochemistry
• immunoprecipitation (1:300)
• fluorescent immunohistochemistry (1:300)
• immunoblotting (1:500)

Biochem/physiol Actions

Humanin (HN) acts as a neuroprotective factor. It is involved in promoting cell survival. Humanin suppresses cell death in the neuronal cells caused by Alzheimer′s disease-related insults like anti-amyloid- precursor protein antibody, neurotoxic amyloid β (Aβ) peptides, and familial Alzheimer disease proteins.

Physical form

Solution of 1 mg/mL in phosphate buffered saline containing 0.02% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: nwg
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable