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Key Documents

G6893

Sigma-Aldrich

α-D-Glucose 1,6-bisphosphate potassium salt hydrate

synthetic, ≥98% (TLC)

Synonym(s):

α-D-Glucose 1,6-diphosphate potassium salt hydrate

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About This Item

Empirical Formula (Hill Notation):
C6H10K4O12P2 · xH2O
CAS Number:
Molecular Weight:
492.48 (anhydrous basis)
MDL number:
UNSPSC Code:
12352201
PubChem Substance ID:
NACRES:
NA.25

biological source

synthetic

Assay

≥98% (TLC)

form

powder or crystals

color

white

solubility

water: 50 mg/mL, clear, colorless (OECD Test Guideline 105)

cation traces

K: 28.5-33.5% (ICP)

storage temp.

−20°C

SMILES string

[K+].[K+].[K+].[K+].O[C@H]1[C@H](O)[C@@H](COP([O-])([O-])=O)O[C@H](OP([O-])([O-])=O)[C@@H]1O

InChI

1S/C6H14O12P2.4K/c7-3-2(1-16-19(10,11)12)17-6(5(9)4(3)8)18-20(13,14)15;;;;/h2-9H,1H2,(H2,10,11,12)(H2,13,14,15);;;;/q;4*+1/p-4/t2-,3-,4+,5-,6-;;;;/m1..../s1

InChI key

OVRXVCAVDXBPQT-QMKHLHGBSA-J

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General description

α-D-Glucose 1,6-bisphosphate was found to be at a concentration of between 10 μm and 600 μm in various tissues including liver, brain and kidney.

Application

α-D-Glucose 1,6-bisphosphate is used in the identification, differentiation and characterization of α-phosphoglucomutase(s), β-phosphoglucomutase(s) and α- and β-hexoglucomutase(s).

Biochem/physiol Actions

Metabolite formed via the activity of Glucose-1,6-biphosphate synthase. Glucose-1,6-biphosphate (G-1,6-BP) acts as an inhibitor of hexokinase function and an activator of phosphofructokinase-1 and pyruvate kinase. G-1,6-BP also acts as a coenzyme for phosphoglucomutate and a cofactor for phosphopentomutase.

Other Notes

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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A kinetic study of the isozymes determined by the three human phosphoglucomutase loci PGM1, PGM2, and PGM3.
C B Quick et al.
European journal of biochemistry, 42(2), 511-517 (1974-03-01)

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