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Key Documents

AV100692

Sigma-Aldrich

Anti-TCEB3 antibody produced in rabbit

IgG fraction of antiserum

Synonym(s):

Anti-Transcription elongation factor B (SIII), polypeptide 3 (110 kDa, elongin A)

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

IgG fraction of antiserum

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

87 kDa

species reactivity

human, dog

concentration

0.5 mg - 1 mg/mL

technique(s)

immunohistochemistry: suitable
western blot: suitable

NCBI accession no.

NP_003189

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... TCEB3(6924)

Immunogen

Synthetic peptide directed towards the C terminal region of human TCEB3

Application

Anti-TCEB3 antibody produced in rabbit is suitable for western blotting at a working concentration of 7.5 μg/ml. The recommended concentration for immunohistochemistry of paraffin-embedded tissue sections is 4-8 μg/ml.

Biochem/physiol Actions

Transcription elongation factor b mediates crosstalk between RNA processing factors, transcription apparatus and the chromatin. This crosstalk results in transcription elongation and optimum production of mRNA.

Sequence

Synthetic peptide located within the following region: AYDGPSTSSAHLAPVVSSTVSYDPRKPTVKKIAPMMAKTIKAFKNRFSRR

Physical form

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Tina Lenasi et al.
RNA biology, 7(2), 145-150 (2010-03-23)
Promoter-proximal pausing of RNA polymerase II (RNAPII) across the genome has renewed our attention to the early transcriptional events that control the establishment of pausing and the release of RNAPII into a productive transcription elongation. Here, we review our current

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