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Key Documents

A3106

Sigma-Aldrich

Apolipoprotein C-III from human plasma

buffered aqueous solution

Synonym(s):

Apo C-III

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About This Item

MDL number:
MFCD00132614
UNSPSC Code:
12352202
NACRES:
NA.61

biological source

human plasma

Quality Level

200

Assay

≥95% (SDS-GE)

form

buffered aqueous solution

mol wt

8.75 kDa

technique(s)

electrophoresis: suitable

UniProt accession no.

P02656

storage temp.

−20°C

Gene Information

human ... APOC3(345)

Biochem/physiol Actions

Apolipoprotein C-III (apoC-III) is central in regulating the metabolism of triglyceride-rich lipoproteins. It is an inhibitor of lipoprotein lipase (LPL). Plasma levels of apoC-III are somewhat correlated to body mass index (BMI) and insulin sensitivity, and strongly correlated to levels of VLDL triglycerides. Reduced levels of apoC-III lead to higher fatty acid uptake of plasma triglycerides into adipose tissue.

Physical form

Solution in 10 mM ammonium bicarbonate.

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Articles

Cholesterol Transport

Since cholesterol is a water-insoluble molecule it must be packaged for transport within the plasma. The particles that package cholesterol, cholesteryl esters, and triglycerides for transport, are called lipoproteins.

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