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Key Documents

Y0000511

Dexamethasone isonicotinate for impurity C identification

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

Dexamethasone 21-isonicotinate

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About This Item

Empirical Formula (Hill Notation):
C28H32FNO6
CAS Number:
Molecular Weight:
497.56
UNSPSC Code:
41116107
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

dexamethasone

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

InChI

1S/C28H32FNO6/c1-16-12-21-20-5-4-18-13-19(31)6-9-25(18,2)27(20,29)22(32)14-26(21,3)28(16,35)23(33)15-36-24(34)17-7-10-30-11-8-17/h6-11,13,16,20-22,32,35H,4-5,12,14-15H2,1-3H3/t16-,20+,21+,22+,25+,26+,27+,28+/m1/s1

InChI key

BQTXJHAJMDGOFI-NJLPOHDGSA-N

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Dexamethasone isonicotinate for impurity C identification EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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[Notes on the disaster in Bhopal].
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Thomas Wittek et al.
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The objective of the study was to describe the effects of a short acting glucocorticoid which was administered immediately after parturition in dairy cows on haematological, immunologic and metabolic parameters. The study was performed on 104 cows, 52 cows received
C Popescu et al.
Revista de igiena, bacteriologie, virusologie, parazitologie, epidemiologie, pneumoftiziologie. Pneumoftiziologia, 30(4), 225-230 (1981-10-01)
Corticoid therapy with dosed aerosols is one of the achievements that have been made lately in the treatment of bronchial asthma. In view of establishing the efficiency of this type of treatment two preparations have been used: Auxiloson (isonicotinate of
M Kusenda et al.
Journal of veterinary internal medicine, 27(1), 200-206 (2012-12-01)
Dexamethasone frequently is used for treatment of ketosis in dairy cows, but its effects are not fully understood. Dexamethasone treatment affects whole body insulin sensitivity. Twelve German Holstein cows, 2-4 weeks postpartum, 5 days after omentopexy to correct left abomasal

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