PHR1053

Albuterol sulfate

Pharmaceutical Secondary Standard; Certified Reference Material

• Synonym(s): Albuterol Sulfate
• Empirical Formula (Hill Notation): C₂₆H₄₄N₂O₁₀S
• CAS Number: 51022-70-9
• Molecular Weight: 576.70
• EC Number: 256-916-8
• UNSPSC Code: 41116107
• PubChem Substance ID: 329823083
• NACRES: NA.24

Properties

• grade: certified reference material; pharmaceutical secondary standard
• Quality Level: 300
• Agency: traceable to BP 302; traceable to Ph. Eur. S0150000; traceable to USP 1012633
• API family: albuterol, salbutamol
• CofA: current certificate can be downloaded
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• application(s): pharmaceutical (small molecule)
• format: neat
• storage temp.: 2-30°C
• Gene Information: human ... ADRB2(154)

Description

General description

Albuterol sulfate is a β₂ adrenergic agonist and a bronchodilating agent, which is used in the treatment of asthma.

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

Albuterol sulfate may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by ultra-performance liquid chromatographic method with ultraviolet detection (UPLC-UV).

Albuterol sulfate may be used as a reference standard in determining the concentration of albuterol sulfate present in inhalers using reversed-phase high performance liquid chromatography (RP-HPLC).

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAA7128 in the slot below. This is an example certificate only and may not be the lot that you receive.

Recommended products

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Safety Information

• Pictograms: GHS08,GHS07
• Signal Word: Warning
• Hazard Statements: H317,H351,H361fd
• Precautionary Statements: P202 - P261 - P272 - P280 - P302 + P352 - P308 + P313
• Hazard Classifications: Carc. 2 - Repr. 2 - Skin Sens. 1
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable