8.56053
H-Gly-2-ClTrt resin
Novabiochem®
Synonym(s):
Glycine-2-Chlorotrityl Resin
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About This Item
UNSPSC Code:
12352209
NACRES:
NA.22
Recommended Products
Quality Level
product line
Novabiochem®
form
beads
reaction suitability
reaction type: Fmoc solid-phase peptide synthesis
manufacturer/tradename
Novabiochem®
application(s)
peptide synthesis
storage temp.
2-8°C
General description
Pre-loaded resin for synthesis of protected peptide acids containing a C-terminal glycine amino-acid residue by Fmoc SPPS. Cleavage of the protected peptide is effected by treatment with 1% TFA in DCM or 20% TFE in DCM
Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS
Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS
Application
- Development of peg-peptide conjugate based curcumin delivery systems: Discusses the use of H-Gly-2-ClTrt resin and Rink amide MBHA resin to synthesize side-chain-protected and deprotected peptides, highlighting challenges in synthesizing high-molecular-weight peptides using 2-chlorotrityl resin. (G Aydoğan, 2022).
Linkage
Replaces: 04-12-2800
Analysis Note
Color (visual): white to yellow to beige
Appearance of substance (visual): beads
Loading (determined from the substitution of the Fmoc-Leu loaded resin): 0.30 - 0.90 mmol/g
Swelling Volume (in DMF): lot specific result
Identity (of the substitution): passes test
The polymer matrix is copoly (styrene-1 % DVB), 200 - 400 mesh.
Appearance of substance (visual): beads
Loading (determined from the substitution of the Fmoc-Leu loaded resin): 0.30 - 0.90 mmol/g
Swelling Volume (in DMF): lot specific result
Identity (of the substitution): passes test
The polymer matrix is copoly (styrene-1 % DVB), 200 - 400 mesh.
Legal Information
Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany
Storage Class Code
11 - Combustible Solids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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