8.51069
2-Biotinyldimedone
Novabiochem®
Synonym(s):
2-Biotinyldimedone
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About This Item
Empirical Formula (Hill Notation):
C18H26N2O4S
CAS Number:
Molecular Weight:
366.48
UNSPSC Code:
12352005
Quality Level
product line
Novabiochem®
Assay
≥98% (TLC)
≥98.0% (HPLC)
form
powder
reaction suitability
reaction type: Biotinylations
manufacturer/tradename
Novabiochem®
application(s)
peptide synthesis
storage temp.
2-30°C
Related Categories
General description
A reagent for the reversible labeling of peptides with biotin [1]. Labeling of the N-terminal amine of resin-bound peptides is carried out by incubating overnight with excess reagent in DMF. The biotinylated peptide is obtained following TFA cleavage. Removal of the biotin label is effected by treatment with 5% aqueous hydrazine.
Associated Protocols and Technical Articles
Purification of Peptides using Chemoselective Tags
Literature references
[1] B. Kellam, et al. (1997) Tetrahedron Lett., 38, 5391
Associated Protocols and Technical Articles
Purification of Peptides using Chemoselective Tags
Literature references
[1] B. Kellam, et al. (1997) Tetrahedron Lett., 38, 5391
Linkage
Replaces: 01-63-0108
Analysis Note
Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Purity (TLC(011A)): ≥ 98 %
Assay (HPLC, area%): ≥ 98.0 % (a/a)
To see the solvent systems used for TLC of Novabiochem® products please click here.
Appearance of substance (visual): powder
Identity (IR): passes test
Purity (TLC(011A)): ≥ 98 %
Assay (HPLC, area%): ≥ 98.0 % (a/a)
To see the solvent systems used for TLC of Novabiochem® products please click here.
Legal Information
Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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