12667-M

Human Serum Albumin

30% Aqueous Solution

• Synonym(s): Albumin, Human Serum, 30% Aqueous Solution
• CAS Number: 70024-90-7
• MDL number: MFCD00081418
• UNSPSC Code: 12352202

Properties

• Product Name: Albumin, Human Serum, 30% Aqueous Solution,
• biological source: human
• Assay: ≥95% (agarose gel electrophoresis)
• form: liquid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze
• technique(s): cell culture | mammalian: suitable
• storage temp.: 2-8°C
• SMILES string: FC(F)(F)C(F)(F)C(F)(F)F
• InChI: 1S/C3F8/c4-1(5,2(6,7)8)3(9,10)11
• InChI key: QYSGYZVSCZSLHT-UHFFFAOYSA-N

Description

General description

Human serum albumin (HSA) is a soluble, globular, and unglycosylated monomeric protein, which is abundantly found in the plasma. It contains three homologous domains, numbered I, II, and III. Each domain is divided into subdomains A and B comprising common structural motifs. The HSA gene is localized to the human chromosome 4q13.3.

Biochem/physiol Actions

Human serum albumin (HSA) acts as the most important carrier protein for fatty acids, thyroid hormones, and steroids. It serves as a supplement in cell culture medium for the generation of vaccines and pharmaceuticals. HSA acts as a valuable biomarker for diseases, such as severe acute graft-versus-host disease, cancer, and rheumatoid arthritis. It is clinically used to treat serious burn injuries, hemorrhagic shock, hypoproteinemia, and fetal erythroblastosis. HSA is used in biological applications including nano delivery of drugs, carrier of oxygen, and fusion of peptides.

Warning

Toxicity: Standard Handling (A)

Physical form

30% solution in 20 mM Tris-HCl, 0.1% NaN₃, pH 6-8.

Preparation Note

Prepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3