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Merck
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Key Documents

07-410

Sigma-Aldrich

Anti-WAVE2/Scar2 Antibody

serum, Upstate®

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

species reactivity

rat, human

manufacturer/tradename

Upstate®

technique(s)

western blot: suitable

isotype

IgG

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... WASF2(10163)

Specificity

WAVE2/Scar2

Immunogen

peptide corresponding to amino acids 186-200 of human WAVE2/Scar2, with an N-terminal cysteine

Application

Research Category
Signaling
Research Sub Category
Cytoskeletal Signaling
This Anti-WAVE2/Scar2 Antibody is validated for use in WB for the detection of WAVE2/Scar2.

Quality

routinely evaluated by immunoblot in in RIPA lysates from HL60 cells

Target description

~68kDa

Physical form

0.05% sodium azide before the addition of glycerol to 30%
Antiserum

Storage and Stability

2 years at -20°C

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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L M Machesky et al.
Current biology : CB, 8(25), 1347-1356 (1999-01-16)
The actin-related proteins Arp2 and Arp3 are part of a seven-protein complex which is localized in the lamellipodia of a variety of cell types, and in actin-rich spots of unknown function. The Arp2/3 complex enhances actin nucleation and causes branching
S Suetsugu et al.
Biochemical and biophysical research communications, 260(1), 296-302 (1999-06-25)
WAVE/SCAR protein was identified as a protein which has similarity to WASP and N-WASP, especially in its C terminal. Recently, WAVE/SCAR protein has been shown to cooperate with the Arp2/3 complex, a nucleation core for actin polymerization in vitro. However

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