N-106

Naltrexone-3-β-D-glucuronide solution

100 μg/mL in methanol, certified reference material, ampule of 1 mL, Cerilliant^®

• Empirical Formula (Hill Notation): C₂₆H₃₁NO₁₀
• CAS Number: 76630-71-2
• Molecular Weight: 517.53
• UNSPSC Code: 41116107
• NACRES: NA.24

Properties

• grade: certified reference material
• Quality Level: 300
• form: liquid
• feature: Snap-N-Spike^®/Snap-N-Shoot^®
• packaging: ampule of 1 mL
• manufacturer/tradename: Cerilliant^®
• concentration: 100 μg/mL in methanol
• technique(s): gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• application(s): forensics and toxicology
• format: single component solution
• shipped in: wet ice
• storage temp.: −20°C
• SMILES string: N2([C@H]3[C@]4([C@@]5([C@@H](Oc6c5c(ccc6O[C@@H]7O[C@@H]([C@H]([C@@H]([C@H]7O)O)O)C(=O)O)C3)C(=O)CC4)CC2)O)CC1CC1
• InChI: 1S/C26H31NO10/c28-13-5-6-26(34)15-9-12-3-4-14(35-24-19(31)17(29)18(30)21(37-24)23(32)33)20-16(12)25(26,22(13)36-20)7-8-27(15)10-11-1-2-11/h3-4,11,15,17-19,21-22,24,29-31,34H,1-2,5-10H2,(H,32,33)/t15-,17+,18+,19-,21+,22+,24-,25+,26-/m1/s1
• InChI key: KCSKQJYZSCIQRR-ODTDCTFRSA-N

Description

General description

A certified solution standard of Naltrexone-3-ß-D-glucuronide, a metabolite of the opiate Naltrexeone. Sold under the trade names Revia, Depade and Vivitrol, naltrexone is prescribed primarily for the management of alcohol or opiate dependence. This analytical reference standard is applicable for use in LC/MS or GC/MS applications such as pharmaceutical research, forensic analysis, clinical toxicology, pain prescription monitoring or urine drug testing.

Application

• Naltrexone in Opioid Dependence: Investigation into multiple-dose pharmacokinetics of a novel analgesic formula incorporating Naltrexone in dogs provided insights into its potential applications in veterinary medicine and possible implications for human medicine, especially concerning opioid dependence and pain management (KuKanich et al., 2021).

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Pictograms: GHS02,GHS06,GHS08
• Signal Word: Danger
• Hazard Statements: H225,H301 + H311 + H331,H370
• Precautionary Statements: P210 - P233 - P280 - P301 + P310 - P303 + P361 + P353 - P304 + P340 + P311
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• Target Organs: Eyes,Central nervous system
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 2
• Flash Point(F): 49.5 °F - closed cup
• Flash Point(C): 9.7 °C - closed cup