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Key Documents

NCXAUNR4010S

Sigma-Aldrich

Gold Nanospheres

40 nm, for Conjugation, Bioready, Dried, NHS, Small Reaction Kit (with 10 Spin Filters), kit of 10 units

Synonym(s):

Gold Nanospheres

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About This Item

UNSPSC Code:
12162002
NACRES:
NA.23

form

nanospheres

packaging

kit of 10 units

particle size

40 nm

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General description

"For updated SDS information please visit nanocomposix.com"

Application

Owing to their plasmonic properties nanoparticles of gold and silver find broad range of applications extending from diagnostics to molecular detection, photothermal and microwave-based therapies, and nanotoxicology. Colloidal silver nanoparticles also find applications in antimicrobial coatings, electronics and photovoltaics, and surface enhanced Raman spectroscopy (SERS) whereas the colloidal gold nanoparticles find applications in lateral flow assays (immunochromatographic assays) and as TEM labels and size standards.

Our BioReady materials are engineered for reliable conjugation with antibodies, proteins, peptides, and other biomolecules and are ideal for lateral flow (immunochromatographic assays) and other diagnostics related applications.

The BioReady spherical gold nanoparticles with carboxyl surface can be used for robust covalent conjugation. This allows for greater stability, sensitivity, reproducibility, and control over particle antibody loading (often requires less antibody compared to passive adsorption). Our covalently-bound streptavidin conjugated gold nanoparticles allow easy binding with biotin.

The BioReady conjugation kits contain dried gold nanoparticles with NHS-activated carboxyl surface. With pre-functionalized nanoparticles with EDC/NHS surface, these are well suited for rapid antibody screening.
The small reaction NHS kits contain 50 μL of 20 OD gold in each unit whereas the large reaction kits contain 500 μL of 20 OD gold in each unit.

Storage and Stability

Carboxyl and Streptavidin: DO NOT FREEZE. Store at 2-8C when not in use to maximize shelf life. Nanomaterials can be sensitive to high and low pH conditions and high salt concentrations. Use caution when changing environmental conditions as particles may aggregate.

NHS Dried material: Store at -20C. Avoid freeze-thaw cycles. Note: NHS material is shipped ambient but should be placed in the freezer upon arrival. Sonicate to resuspend. Store additional kit components according to their labels.

Legal Information

Product of nanoComposix, Inc.

Signal Word

Danger

Hazard Statements

H317,H318,H351,H412

Hazard Classifications

Aquatic Chronic 3 - Carc. 2 - Eye Dam. 1 - Skin Sens. 1

Storage Class Code

10 - Combustible liquids

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Articles

Gold Nanoparticles for Biomolecular Diagnostics

Drs. Fernandes and Baptista explore the synthesis and functionalization of gold nanoparticles and their use in molecular diagnostics, focusing on lateral flow assays. They further discuss the regulations and standards of these materials, as well as the future outlook and challenges.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

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