900762

Sodium 4-(trifluoromethyl)pyridine-2-sulfinate

≥95%

• Synonym(s): Willis 4-trifluoromethyl pyridine 2-sulfinate
• Empirical Formula (Hill Notation): C₆H₃F₃NNaO₂S
• Molecular Weight: 233.14
• UNSPSC Code: 12352200

Properties

• Assay: ≥95%
• form: powder or crystals
• reaction suitability: reaction type: C-C Bond Formation

Description

Application

This 2-pyridylsulfinate enables Suzuki-Miyaura cross coupling with aryl halides to access diverse pyridine derivatives as reported by the laboratory of Michael Willis.. No longer impeded by unstable 2-pyridyl boronates, the sulfinate alternatives provide Pd-catalyzed coupling routes to therapeutically valuable pyridine rings.

Other Notes

• Technology Spotlight: Willis Pyridinates for Palladium-Catalyzed Cross-Coupling Reactions.
• Pyridine Sulfinates as General Nucleophilic Coupling Partners in Palladium-Catalyzed Cross-Coupling Reactions with Aryl Halides

Safety Information

• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable