70430
1,4-Dihydroxynaphthalene
technical, ≥90% (HPLC)
Synonym(s):
1,4-Naphthalenediol, p-Naphthohydroquinone (α)
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About This Item
Recommended Products
grade
technical
Quality Level
Assay
≥90% (HPLC)
form
crystals
mp
191-192 °C (dec.)
SMILES string
Oc1ccc(O)c2ccccc12
InChI
1S/C10H8O2/c11-9-5-6-10(12)8-4-2-1-3-7(8)9/h1-6,11-12H
InChI key
PCILLCXFKWDRMK-UHFFFAOYSA-N
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Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Autoxidation of naphthohydroquinones: effects of metals, chelating agents, and superoxide dismutase.
Free radical biology & medicine, 22(4), 689-695 (1997-01-01)
At neutral pH, 1,4-naphthohydroquinone and 2-methyl-1,4-naphthohydroquinone readily autoxidize to the corresponding quinones. In an unpurified phosphate buffer, the autoxidation of both substances proceeded in a linear fashion after a brief lag phase. Addition of a chelating agent or purification of
Free radical research, 32(3), 245-253 (2000-03-24)
The rates of autoxidation of a number of pure naphthohydroquinones have been determined, and the effects of pH, superoxide dismutase (SOD) and of the parent naphthoquinone on the oxidation rates have been investigated. Most compounds were slowly oxidised in acid
Selective nonpeptidic inhibitors of herpes simplex virus type 1 and human cytomegalovirus proteases.
Biological & pharmaceutical bulletin, 24(3), 236-241 (2001-03-21)
The proteases encoded by herpesviruses including herpes simplex virus type 1 (HSV-1) and human cytomegalovirus (HCMV) are attractive targets for antiviral drug development because of their important roles in viral replication. We randomly screened a chemical compound library for inhibitory
The Journal of organic chemistry, 74(24), 9573-9575 (2009-11-27)
The NHC-catalyzed conjugate hydroacylation of 1,4-naphthoquinones allows for the synthesis of monoacylated 1,4-dihydroxynaphthalene derivatives. These targets, difficult to prepare selectively by standard protocols, represent important intermediates in the elaboration of highly substituted 1,4-naphthoquinone derivatives, which constitute relevant pharmaceutical scaffolds. High
Free radical biology & medicine, 8(1), 21-24 (1990-01-01)
The autoxidation of 1,4-naphthohydroquinone, in a phosphate, EDTA buffer at pH 7.4, exhibits an autocatalysis whose lag phase becomes more pronounced in the presence of either the Cu,Zn- or the Mn-containing superoxide dismutases. In contrast, the autoxidation of a second
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