703788

Sodium tert-butoxide

99.9%

• Synonym(s): Sodium 2-methylpropan-2-olate, Sodium t-butoxide, Sodium tert-butanolate, Sodium tert-butylate
• Linear Formula: NaOC(CH₃)₃
• CAS Number: 865-48-5
• Molecular Weight: 96.10
• Beilstein: 3654215
• EC Number: 212-741-9
• MDL number: MFCD00040575
• UNSPSC Code: 12352107
• PubChem Substance ID: 329762066
• NACRES: NA.22

Properties

• Quality Level: 200
• Assay: 99.9%
• form: powder
• density: 1.025 g/cm³ at 68 °F
• SMILES string: [Na+].CC(C)(C)[O-]; [Na+].CC(C)(C)[O-]
• InChI: 1S/C4H9O.Na/c1-4(2,3)5;/h1-3H3;/q-1;+1; 1S/C4H9O.Na/c1-4(2,3)5;/h1-3H3;/q-1;+1
• InChI key: MFRIHAYPQRLWNB-UHFFFAOYSA-N; MFRIHAYPQRLWNB-UHFFFAOYSA-N

Description

Application

Sodium tert-butoxide can be used as:

• A promoter for the synthesis of biaryls by C-H bond arylation of aromatic compounds with haloarenes.
• A base in palladium catalyzed amination reactions.
• A base in the synthesis of aryl tert-butyl ethers from unactivated aryl halides in presence of palladium catalyst.
• In the desulfonylation of N-indoles and N-azaindoles.
• As a base in the synthesis of sodium acrylates from olefins and CO₂.

Safety Information

• Pictograms: GHS02,GHS05
• Signal Word: Danger
• Hazard Statements: H228,H251,H314
• Precautionary Statements: P210 - P235 - P260 - P280 - P303 + P361 + P353 - P305 + P351 + P338
• Hazard Classifications: Eye Dam. 1 - Flam. Sol. 1 - Self-heat. 1 - Skin Corr. 1B
• Supplementary Hazards: EUH014
• Storage Class Code: 4.2 - Pyrophoric and self-heating hazardous materials
• WGK: WGK 1
• Flash Point(F): 57.2 °F
• Flash Point(C): 14 °C