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Sigma-Aldrich

Poly(ethylene glycol) diacrylate

average Mn 250

Synonym(s):

Polyethylene glycol, PEG diacrylate

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About This Item

CAS Number:
26570-48-9
MDL number:
MFCD00081876
UNSPSC Code:
12162002
PubChem Substance ID:
24871153
NACRES:
NA.23

mol wt

average Mn 250

Quality Level

100

contains

100 ppm MEHQ as inhibitor

reaction suitability

reagent type: cross-linking reagent
reaction type: Polymerization Reactions

refractive index

n20/D 1.463

density

1.11 g/mL at 25 °C

Ω-end

acrylate

α-end

acrylate

polymer architecture

shape: linear
functionality: homobifunctional

storage temp.

2-8°C

SMILES string

OCCO.OC(=O)C=C

InChI

1S/C8H10O4/c1-3-7(9)11-5-6-12-8(10)4-2/h3-4H,1-2,5-6H2

InChI key

KUDUQBURMYMBIJ-UHFFFAOYSA-N

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General description

Poly(ethylene glycol) diacrylate (PEGDA) is a polyethylene glycol (PEG) based material that can be used for a variety of tissue engineering and drug delivery based applications. It is majorly used as a prepolymer solution that can be used in the formation of a cross-linked polymeric system.

Application

PEGDA can be used in the formation of a UV-cured membrane for potential usage in the separation of carbon dioxide (CO2) based gases. It may also be used in the development of novel injectable biodegradable polymers for a variety of biomedical applications.

Pictograms

CorrosionExclamation mark
GHS05,GHS07

Signal Word

Danger

Hazard Statements

H315 - H317 - H318

Hazard Classifications

Eye Dam. 1 - Skin Irrit. 2 - Skin Sens. 1

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Multifunctional thiols as additives in UV-cured PEG-diacrylate membranes for CO2 separation
Kwisnek L, et al.
Journal of Membrane Science, 369(1-2), 429-436 (2011)
Injectable biodegradable polymer composites based on poly (propylene fumarate) crosslinked with poly (ethylene glycol)-dimethacrylate
He S, et al.
Biomaterials, 21(23), 2389-2394 (2000)
Preparation and characterization of crosslinked poly (ethylene glycol) diacrylate hydrogels as fouling-resistant membrane coating materials
Ju H, et al.
Journal of Membrane Science , 330(1-2), 180-188 (2009)
Release of protein from highly cross-linked hydrogels of poly (ethylene glycol) diacrylate fabricated by UV polymerization
Mellott MB, et al.
Biomaterials, 22(9), 929-941 (2001)
Hyeong Jun Kim et al.
Science (New York, N.Y.), 367(6479), 773-776 (2020-02-15)
Soft ionic conductors have enabled stretchable and transparent devices, but liquids in such devices tend to leak and evaporate. In this study, we demonstrate diodes and transistors using liquid-free ionoelastomers, in which either anions or cations are fixed to an

Articles

Patterning of PEG-based Hydrogels - Engineering Spatial Complexity

In this article, we will discuss the benefits and limitations of several 2D and 3D scaffold patterning techniques that can be applied in the presence of cells. Although these methods will be discussed in the context of poly(ethylene glycol) (PEG)-based hydrogels, they can technically be applied to any optically transparent, photoactive substrate.

Degradable Poly(ethylene glycol) Hydrogels for 2D and 3D Cell Culture

Progress in biotechnology fields such as tissue engineering and drug delivery is accompanied by an increasing demand for diverse functional biomaterials. One class of biomaterials that has been the subject of intense research interest is hydrogels, because they closely mimic the natural environment of cells, both chemically and physically and therefore can be used as support to grow cells. This article specifically discusses poly(ethylene glycol) (PEG) hydrogels, which are good for biological applications because they do not generally elicit an immune response. PEGs offer a readily available, easy to modify polymer for widespread use in hydrogel fabrication, including 2D and 3D scaffold for tissue culture. The degradable linkages also enable a variety of applications for release of therapeutic agents.

Versatile Cell Culture Scaffolds via Bio-orthogonal Click Reactions

Devising biomaterial scaffolds that are capable of recapitulating critical aspects of the complex extracellular nature of living tissues in a threedimensional (3D) fashion is a challenging requirement in the field of tissue engineering and regenerative medicine.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

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