Skip to Content
Merck
All Photos(1)

Key Documents

View All Documentation

372951

Sigma-Aldrich

tert-Butyldimethylsilyl chloride solution

1.0 M in THF

Synonym(s):

tert-Butylchlorodimethylsilane solution, tert-Butyldimethylchlorosilane, tert-Butyldimethylsilyl chloride, TBDMSCl solution

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Linear Formula:
(CH3)3CSi(CH3)2Cl
CAS Number:
18162-48-6
Molecular Weight:
150.72
Beilstein:
505999
MDL number:
MFCD00000501
UNSPSC Code:
12352103
PubChem Substance ID:
24863185
NACRES:
NA.22

form

liquid

Quality Level

100

concentration

1.0 M in THF

density

0.87 g/mL at 20 °C (lit.)
0.879 g/mL at 25 °C

SMILES string

CC(C)(C)[Si](C)(C)Cl

InChI

1S/C6H15ClSi/c1-6(2,3)8(4,5)7/h1-5H3

InChI key

BCNZYOJHNLTNEZ-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Related Categories

related product

Product No.
Description
Pricing

19905

tert-Butyl(chloro)dimethylsilane, ≥95.0% (GC)

394882

N-tert-Butyldimethylsilyl-N-methyltrifluoroacetamide, >97%

190500

tert-Butyldimethylsilyl chloride, reagent grade, 97%

375934

N-tert-Butyldimethylsilyl-N-methyltrifluoroacetamide with 1% tert-Butyldimethylchlorosilane, ≥95%

473464

tert-Butylchlorodimethylsilane solution, 50 wt. % in toluene

384429

tert-Butyldimethylsilyl chloride solution, 1.0 M in methylene chloride

226149

tert-Butyldimethylsilyl trifluoromethanesulfonate, reagent grade, 98%

250236

1-(tert-Butyldimethylsilyl)imidazole, ≥95%

33092-U

tert-Butyldimethylsilylimidazole solution, TBDMSIM in DMF, pkg of 10 × 1 mL

06735

tert-Butyldimethylsilyl chloride, for GC derivatization, LiChropur™, ≥99.0% (GC)

56563

tert-Butyldimethylsilyl trifluoromethanesulfonate, for GC derivatization, LiChropur™, ≥98.0% (T)

77626

N-tert-Butyldimethylsilyl-N-methyltrifluoroacetamide, for GC derivatization, LiChropur™, ≥98.0% (GC)

00942

N-tert-Butyldimethylsilyl-N-methyltrifluoroacetamide with 1% tert-Butyldimethylchlorosilane, for GC derivatization, LiChropur™, ≥95.0% (GC)

44795

N,O-Bis(tert-butyldimethylsilyl)acetamide, for GC derivatization, LiChropur™, ≥98.0% (GC)

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1A - STOT SE 3

Target Organs

Central nervous system, Respiratory system

Supplementary Hazards

EUH019

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

1.4 °F - closed cup

Flash Point(C)

-17 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
MKCN7348
SHBK9979
SHBK2140
SHBH2385V
SHBD0295V

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Akshanth R Polepally et al.
Journal of clinical pharmacology, 55(10), 1101-1108 (2015-04-24)
A classic 2-period crossover bioavailability study was conducted to evaluate the relative and absolute bioavailability of immediate-release (IR) and extended-release (XR) lamotrigine formulations under steady-state conditions in elderly patients with epilepsy. On treatment days, each subject's morning dose (IR or
Hiroaki Wakimoto et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 20(11), 2898-2909 (2014-04-10)
Isocitrate dehydrogenase (IDH) gene mutations occur in low-grade and high-grade gliomas. We sought to identify the genetic basis of malignant phenotype heterogeneity in IDH-mutant gliomas. We prospectively implanted tumor specimens from 20 consecutive IDH1-mutant glioma resections into mouse brains and
Some observations on the t-butyldimethylchlorosilane derivatization reaction.
K Bricknell et al.
Biochemical medicine, 23(1), 119-121 (1980-02-01)
Grethe M Olsen et al.
Neurochemistry international, 88, 47-52 (2014-12-03)
Pyruvate carboxylation, the anaplerotic reaction in the brain, has been demonstrated in astrocytes but not neurons. Since anaplerosis cannot proceed without cataplerosis in a closed system such as the brain, there have to be mechanisms to degrade molecules such as
Rie Harboe Nielsen et al.
Journal of applied physiology (Bethesda, Md. : 1985), 117(7), 694-698 (2014-08-12)
The classic form of Ehlers-Danlos syndrome (cEDS) is an inherited connective tissue disorder, where mutations in type V collagen-encoding genes result in abnormal collagen fibrils. Thus the cEDS patients have pathological connective tissue morphology and low stiffness, but the rate
View All Related Papers

Global Trade Item Number

SKUGTIN
372951-100ML4061831834369

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service