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270873

Sigma-Aldrich

2-Hydroxyquinoline

98%

Synonym(s):

2-Quinolinol, Carbostyril

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About This Item

Empirical Formula (Hill Notation):
C9H7NO
CAS Number:
59-31-4
Molecular Weight:
145.16
EC Number:
200-420-6
MDL number:
MFCD00006743
UNSPSC Code:
12352100
PubChem Substance ID:
24856409
NACRES:
NA.22

Assay

98%

form

crystals

mp

198-199 °C (lit.)

solubility

alcohol: soluble(lit.)
diethyl ether: soluble(lit.)
dilute HCl: soluble(lit.)
water: slightly soluble (1 g/950mL)(lit.)

SMILES string

Oc1ccc2ccccc2n1

InChI

1S/C9H7NO/c11-9-6-5-7-3-1-2-4-8(7)10-9/h1-6H,(H,10,11)

InChI key

LISFMEBWQUVKPJ-UHFFFAOYSA-N

General description

2-Hydroxyquinoline is a specific inhibitor of plaque paraoxonase1 (PON1).

Application

2-Hydroxyquinoline was used to obtain the design of the platinum(IV) complexes with intense bands shifted towards longer wavelengths. The Pt(IV) complexes are inert stable prodrugs that were photoactivated to produce Pt(II) species with promising anticancer activity.

Pictograms

CorrosionExclamation mark
GHS05,GHS07

Signal Word

Danger

Hazard Statements

H302,H315,H318,H335

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Hui-Chung Tai et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 18(34), 10630-10642 (2012-07-19)
Diazido Pt(IV) complexes are inert stable prodrugs that can be photoactivated to produce Pt(II) species with promising anticancer activity. Our studies of the photochemistry of Pt(IV) complexes, [Pt(X)(2) (Y)(2) (Z)(2) ](0/-1) (X=N-ligands (NH(3) , pyridine, etc.)/S(CH(3) )(2) /H(-) , Y=(pseudo)halogen
Kaitlyn M Ferguson et al.
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