175501

Boron trifluoride diethyl etherate

for synthesis

• Synonym(s): Boron trifluoride ethyl etherate
• Linear Formula: BF₃ · O(C₂H₅)₂
• CAS Number: 109-63-7
• Molecular Weight: 141.93
• Beilstein: 3909607
• EC Number: 203-689-8
• MDL number: MFCD00013194
• UNSPSC Code: 12352106
• PubChem Substance ID: 24850505
• NACRES: NA.22

Properties

• grade: for synthesis
• Quality Level: 200
• vapor density: 4.9 (vs air)
• vapor pressure: 4.2 mmHg ( 20 °C)
• form: liquid
• expl. lim.: 36 %
• reaction suitability: core: boron; reagent type: Lewis acid; reagent type: catalyst
• refractive index: n20/D 1.344 (lit.)
• bp: 126-129 °C (lit.)
• mp: −58 °C (lit.)
• density: 1.15 g/mL (lit.)
• storage temp.: 2-8°C
• SMILES string: CC[O+](CC)[B-](F)(F)F
• InChI: 1S/C4H10BF3O/c1-3-9(4-2)5(6,7)8/h3-4H2,1-2H3
• InChI key: MZTVMRUDEFSYGQ-UHFFFAOYSA-N

Description

General description

Boron trifluoride diethyl etherate or boron trifluoride-ether complex is an organic compound widely used as a convenient source of boron trifluoride (BF₃) in organic synthesis. It is also used as a Lewis acid for the activation of electrophiles.

Application

Catalyst used in the preparation of cyclopentyl- and cycloheptyl[b]indoles from aryl cyclopropyl ketones via [3+2] cycloaddition.

Lewis acid reagent with broad application

Packaging

The 25 mL Sure/Seal^™ bottle is recommended as a single-use bottle. Repeated punctures will likely result in decreased performance of product.

Legal Information

Sure/Seal is a trademark of Sigma-Aldrich Co. LLC

Safety Information

• Pictograms: GHS02,GHS08,GHS05,GHS07
• Signal Word: Danger
• Hazard Statements: H226,H302 + H332,H314,H372
• Precautionary Statements: P210 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P314
• Hazard Classifications: Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - Flam. Liq. 3 - Skin Corr. 1B - STOT RE 1 Inhalation
• Target Organs: Kidney
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 1
• Flash Point(F): 137.3 °F - closed cup
• Flash Point(C): 58.5 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves