1670207

Tolcapon

United States Pharmacopeia (USP) Reference Standard

• Synonym(e): 3,4-Dihydroxy-4′-methyl-5-nitrobenzophenon, Ro 40-7592
• Empirische Formel (Hill-System): C₁₄H₁₁NO₅
• CAS-Nummer: 134308-13-7
• Molekulargewicht: 273.24
• MDL-Nummer: MFCD00866569
• UNSPSC-Code: 41116107
• PubChem Substanz-ID: 329751344
• NACRES: NA.24

Eigenschaften

• Qualität: pharmaceutical primary standard
• API-Familie: tolcapone
• Hersteller/Markenname: USP
• Anwendung(en): pharmaceutical (small molecule)
• Format: neat
• SMILES String: Cc1ccc(cc1)C(=O)c2cc(O)c(O)c(c2)[N+]([O-])=O
• InChI: 1S/C14H11NO5/c1-8-2-4-9(5-3-8)13(17)10-6-11(15(19)20)14(18)12(16)7-10/h2-7,16,18H,1H3
• InChIKey: MIQPIUSUKVNLNT-UHFFFAOYSA-N
• Angaben zum Gen: human ... COMT(1312)

Beschreibung

Allgemeine Beschreibung

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Anwendung

Tolcapone USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Tolcapone Tablets

Biochem./physiol. Wirkung

Tolcapone is an orally active catechol-O-methyltransferase (COMT) inhibitor. It inhibits both central and peripheral COMT. Tolcapone crosses the blood-brain barrier, and has been used for L-DOPA adjunct therapy in the treatment of Parkinson′s Disease.

Hinweis zur Analyse

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Sonstige Hinweise

Sales restrictions may apply.

Sicherheitshinweise

• Piktogramme: GHS09
• Signalwort: Warning
• H-Sätze: H400
• P-Sätze: P273 - P391 - P501
• Gefahreneinstufungen: Aquatic Acute 1
• Lagerklassenschlüssel: 11 - Combustible Solids
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable