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1576005

USP

Propranolol -hydrochlorid

United States Pharmacopeia (USP) Reference Standard

Synonym(e):

(±)-Propranolol -hydrochlorid, (±)-1-Isopropylamino-3-(1-naphthyloxy)-2-propanol -hydrochlorid, DL-Propranolol -hydrochlorid

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About This Item

Empirische Formel (Hill-System):
C16H21NO2 · HCl
CAS-Nummer:
318-98-9
Molekulargewicht:
295.80
Beilstein:
4164259
MDL-Nummer:
MFCD00012558
UNSPSC-Code:
41116107
PubChem Substanz-ID:
329750990
NACRES:
NA.24

Qualität

pharmaceutical primary standard

API-Familie

propranolol

Hersteller/Markenname

USP

Anwendung(en)

pharmaceutical (small molecule)

Format

neat

SMILES String

Cl.CC(C)NCC(O)COc1cccc2ccccc12

InChI

1S/C16H21NO2.ClH/c1-12(2)17-10-14(18)11-19-16-9-5-7-13-6-3-4-8-15(13)16;/h3-9,12,14,17-18H,10-11H2,1-2H3;1H

InChIKey

ZMRUPTIKESYGQW-UHFFFAOYSA-N

Angaben zum Gen

human ... ADRB1(153) , ADRB2(154)

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Allgemeine Beschreibung

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Hinweis zur Analyse

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Sonstige Hinweise

Sales restrictions may apply.

Piktogramme

Exclamation mark
GHS07

Signalwort

Warning

H-Sätze

H302

Gefahreneinstufungen

Acute Tox. 4 Oral

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

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Analysenzertifikate (COA)

Lot/Batch Number

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Atenolol ≥98% (TLC), powder

Sigma-Aldrich

A7655

Atenolol

Canan Akyüz et al.
Pediatric blood & cancer, 61(5), 931-932 (2013-11-23)
Lymphangiomas of the tongue are rare, and their treatment is problematic. A 10 year-old patient with tongue lymphangioma who was previously treated with surgery and propranolol with no response was treated with sirolimus in our department. We used sirolimus with
Katherine B Püttgen
Pediatric clinics of North America, 61(2), 383-402 (2014-03-19)
Propranolol has replaced corticosteroids as preferred first-line therapy for the management of infantile hemangiomas (IH). The topical β-blocker timolol is now an alternative to oral propranolol and watchful waiting for smaller IH. Research in the last decade has provided evidence-based
Pawel Szychta et al.
Plastic and reconstructive surgery, 133(4), 852-862 (2013-12-20)
Infantile hemangioma is a vascular tumor and requires treatment in lesions manifested by potentially dangerous symptoms. Several publications have reported that involution of infantile hemangioma could be accelerated by propranolol but have used only invalidated subjective measures of assessment. The
Dennis D Rasmussen et al.
Alcoholism, clinical and experimental research, 38(6), 1532-1539 (2014-06-04)
Evidence suggests that activation of the noradrenergic system may contribute to alcohol drinking in animals and humans. Our previous studies demonstrated that blocking α1 -adrenergic receptors with the antagonist, prazosin, decreased alcohol drinking in rats under various conditions. As noradrenergic
Alvaro Ábarzúa-Araya et al.
Journal of the American Academy of Dermatology, 70(6), 1045-1049 (2014-03-25)
Infantile hemangiomas have a dramatic response to propranolol, a nonselective beta-blocker. However, this treatment is not risk-free and many patients are excluded because of respiratory comorbidities. Atenolol is a cardioselective beta-blocker that may have fewer adverse events. We sought to
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