1553815

Pramipexol-verwandte Verbindung D

United States Pharmacopeia (USP) Reference Standard

• Synonym(e): Dexpramipexol -dihydrochlorid
• Empirische Formel (Hill-System): C₁₀H₁₇N₃S · 2HCl
• CAS-Nummer: 104632-27-1
• Molekulargewicht: 284.25
• MDL-Nummer: MFCD13186799
• UNSPSC-Code: 41116107
• PubChem Substanz-ID: 329750929
• NACRES: NA.24

Eigenschaften

• Qualität: pharmaceutical primary standard
• API-Familie: pramipexole
• Hersteller/Markenname: USP
• Anwendung(en): pharmaceutical (small molecule)
• Format: neat
• SMILES String: Cl.Cl.CCCN[C@@H]1CCc2nc(N)sc2C1
• InChI: 1S/C10H17N3S.2ClH/c1-2-5-12-7-3-4-8-9(6-7)14-10(11)13-8;;/h7,12H,2-6H2,1H3,(H2,11,13);2*1H/t7-;;/m1../s1
• InChIKey: QMNWXHSYPXQFSK-XCUBXKJBSA-N

Beschreibung

Allgemeine Beschreibung

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Anwendung

Pramipexole Related Compound D USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.

Biochem./physiol. Wirkung

R-(+)-Pramipexole is a neuroprotective agent; weak non-ergoline dopamine agonist. R-(+)-Pramipexole has been found to have neuroprotective effects and is being investigated for treatment of ALS. It reduces mitochondrial reactive oxygen species (ROS) production, inhibits the activation of apoptotic pathways, and increase cell survival in response to a variety of neurotoxins and β-amyloid neurotoxicity. Compared to the S-(-) isomer, R-(+)-Pramipexole has much lower dopamine agonist activity.

Hinweis zur Analyse

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Sonstige Hinweise

Sales restrictions may apply.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H302
• P-Sätze: P301 + P312 + P330
• Gefahreneinstufungen: Acute Tox. 4 Oral
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable