53519-U

Ascentis^® Express 90 Å RP-Amide (2.7 μm) HPLC Columns

L × I.D. 5 mm × 4.6 mm, HPLC Guard Cartridge, pkg of 3 ea

• Synonym(e): Core-shell (SPP) Fused Core polar embedded HPLC column
• UNSPSC-Code: 41115700
• eCl@ss: 32110501
• NACRES: SB.52

Eigenschaften

• product name: Ascentis^® Express RP-Amid, 2,7-μm-Schutzkartusche, 2.7 μm particle size, L × I.D. 5 mm × 4.6 mm, pkg of 3 ea
• Materialien: stainless steel column
• Agentur: suitable for USP L60
• Produktlinie: Ascentis^®
• Leistungsmerkmale: endcapped
• Verpackung: pkg of 3 ea
• Methode(n): HPLC: suitable; LC/MS: suitable
• L × ID: 5 mm × 4.6 mm
• Oberflächenbereich: 135 m²/g
• Matrix: Fused-Core^® particle platform; superficially porous particle
• Aktive Matrixgruppe: amide, alkyl phase
• Partikelgröße: 2.7 μm
• Porengröße: 90 Å
• Betriebs-pH-Wert: 2-9
• Anwendung(en): food and beverages
• Trenntechnik: reversed phase

Beschreibung

Allgemeine Beschreibung

Ascentis Express Vorsäulen bieten physischen (Filtration) und chemischen Schutz für teure Analysesäulen, ohne die sehr hohe Leistung der Ascentis Express Säulen zu beeinträchtigen. Diese Ascentis Express Vorsäulen eignen sich für den Dauereinsatz bei einem Druck von bis zu 600 bar und müssen lediglich handfest angezogen werden. Die Vorsäulen lassen sich mühelos austauschen, ohne den Vorsäulenhalter vom Flusspfad entfernen zu müssen. Die Kartuschen sind mit Ascentis Express Fused-Core^® Partikeln gepackt. Der Vorsäulenhalter ist separat zu bestellen.

Anwendung

• Polycaprolactone Composite Micro/Nanofibrous Material as an Alternative to Restricted Access Media for Direct Extraction and Separation of Non-Steroidal Anti-Inflammatory Drugs from Human Serum Using Column-Switching Chromatography: This research utilized the Ascentis Express RP-Amide, demonstrating its effectiveness in column-switching chromatography for the extraction and separation of non-steroidal anti-inflammatory drugs directly from human serum. The study highlights the column′s utility in handling complex biological matrices, an essential aspect for pharmacokinetic and drug monitoring studies (Raabova et al., 2021).


• An HPLC-MS method for the quantification of new acetylcholinesterase inhibitor PC 48 (7-MEOTA-donepezil like compound) in rat plasma: Application to a pharmacokinetic study: This paper details the use of the Ascentis Express RP-Amide in a validated HPLC-MS method for the analysis of PC 48, a novel acetylcholinesterase inhibitor, in rat plasma. The method′s application to pharmacokinetic studies underscores its significance in the development and therapeutic monitoring of new drugs (Mzik et al., 2016).


• On-line SPE-UHPLC method using fused core columns for extraction and separation of nine illegal dyes in chilli-containing spices: Demonstrating the versatility of the Ascentis Express RP-Amide, this study employed the column in an on-line solid-phase extraction (SPE) coupled with UHPLC to detect illegal dyes in food samples. The method′s robustness and high-throughput capabilities make it ideal for ensuring food safety and compliance with regulatory standards (Khalikova et al., 2014).

Rechtliche Hinweise

Ascentis is a registered trademark of Merck KGaA, Darmstadt, Germany

Fused-Core is a registered trademark of Advanced Materials Technology, Inc.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable