T8819

TFIIB human

~5 units/μL, recombinant, expressed in E. coli, solution

• MDL-Nummer: MFCD01636087
• UNSPSC-Code: 12352202
• NACRES: NA.56

Eigenschaften

• Rekombinant: expressed in E. coli
• Qualitätsniveau: 200
• Form: solution
• Mol-Gew.: ~32 kDa
• Konzentration: ~5 units/μL
• UniProt-Hinterlegungsnummer: Q00403
• Versandbedingung: dry ice
• Lagertemp.: −70°C
• Angaben zum Gen: human ... GTF2B(2959)

Beschreibung

Biochem./physiol. Wirkung

General transcription factor for RNA Polymerase II.

The amino terminal region of TFIIB contains a zinc ribbon fold composed of antiparallel Β strands. Mutational studies show that this domain is required for recruitment of RNA Pol II for transcriptional initiation.

Einheitendefinition

One gel shift unit is the amount of TFIIB required to form 0.2 pmol of TFIIB/TFIID/DNA complex as detected by gel shift.

Physikalische Form

Solution in 20 mM Tris-HCl, pH 7.4, 100 mM NaCl, 2 mM DTT, 1 mM EDTA, 0.1% Triton® X-100.

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves