Direkt zum Inhalt
Merck

T5783

Supelco

2,3,4,6-Tetra-O-acetyl-β-D-glucopyranosyl-isothiocyanat

for chiral derivatization, LiChropur, ≥98.0% (HPLC)

Synonym(e):

GITC

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About This Item

Empirische Formel (Hill-System):
C15H19NO9S
CAS-Nummer:
Molekulargewicht:
389.38
Beilstein:
56699
MDL-Nummer:
UNSPSC-Code:
12000000
PubChem Substanz-ID:
NACRES:
NA.22

Qualität

for chiral derivatization
LiChropur

Assay

≥98.0% (HPLC)

Methode(n)

HPLC: suitable

mp (Schmelzpunkt)

114-116 °C (lit.)

Lagertemp.

2-8°C

SMILES String

CC(=O)OC[C@H]1O[C@@H](N=C=S)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O

InChI

1S/C15H19NO9S/c1-7(17)21-5-11-12(22-8(2)18)13(23-9(3)19)14(24-10(4)20)15(25-11)16-6-26/h11-15H,5H2,1-4H3/t11-,12-,13+,14-,15-/m1/s1

InChIKey

WOWNQYXIQWQJRJ-UXXRCYHCSA-N

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Allgemeine Beschreibung

2,3,4,6-Tetra-O-acetyl-β-D-glucopyranosyl isothiocyanate is a chiral derivatization reagent which reacts mainly with enantiomeric amino acids.

Anwendung

Chirales Reagens für die Trennung von Aminosäure-Derivaten.
GITC may have been used in the formation of diastereomers and for reversed-phase high-performance liquid chromatographic resolution of amino acid enantiomers.

Verpackung

Bottomless glass bottle. Contents are inside inserted fused cone.

Empfohlene Produkte

Discover LiChropur reagents ideal for HPLC or LC-MS analysis

Rechtliche Hinweise

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

Piktogramme

Health hazardExclamation mark

Signalwort

Danger

Gefahreneinstufungen

Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

Zielorgane

Respiratory system

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


Analysenzertifikate (COA)

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Kunden haben sich ebenfalls angesehen

Zhiqiong Chen et al.
Journal of separation science, 28(2), 193-196 (2005-03-10)
Chiral separation of racemic mixtures is of the greatest importance to the pharmaceutical industry, as the isomers of a given racemate may exhibit substantially different pharmacological effects, not to mention possibly differing toxicity behaviour. A novel chiral separation method is
J Gal et al.
Journal of pharmacological methods, 16(3), 261-269 (1986-11-01)
Many established and experimental adrenergic agonists are derivatives of 2-aminoethanol with a phenol or catechol moiety in the 1-position. There is considerable interest in the stereochemical aspects of the actions of such chiral drugs. Surprisingly, however, little has been published
X Li et al.
Journal of chromatography. B, Biomedical sciences and applications, 742(2), 433-439 (2000-07-20)
A reversed-phase high-performance liquid chromatographic method for the determination of the enantiomers of atenolol in rat hepatic microsome has been developed. Racemic atenolol was extracted from alkalinized rat hepatic microsome by ethyl acetate. The organic layer was dried with anhydrous
Sherry Wang et al.
Journal of pharmaceutical and biomedical analysis, 43(2), 701-707 (2006-09-09)
A stable isotopically labeled (SIL) analogue is believed to be the most appropriate internal standard in a quantitative bioanalytical liquid chromatography/tandem mass spectrometry (LC/MS/MS) assay. It is assumed that a SIL internal standard always compensates for variability in chemical derivatization
Klaas E A Max et al.
Proceedings of the National Academy of Sciences of the United States of America, 115(23), E5334-E5343 (2018-05-20)
Circulating extracellular RNAs (exRNAs) have the potential to serve as biomarkers for a wide range of medical conditions. However, limitations in existing exRNA isolation methods and a lack of knowledge on parameters affecting exRNA variability in human samples may hinder

Protokolle

Enantiomeric analysis of neurotransmitters and pharmaceuticals carrying functional amino groups, ß-adrenergic blockers; penicillamine, mexiletine; fine chemicals such as 1-phenyl-2-aminoethanol.

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