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Wichtige Dokumente
T4571
Taurin
Arzneimittelherstellung
Synonym(e):
2-Aminoethansulfonsäure
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About This Item
Lineare Formel:
NH2CH2CH2SO3H
CAS-Nummer:
Molekulargewicht:
125.15
Beilstein:
1751215
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
12352106
NACRES:
NA.26
Empfohlene Produkte
Biologische Quelle
non-animal source
Qualitätsniveau
Assay
≥98.5%
Form
crystalline powder
Methode(n)
cell culture | mammalian: suitable
Verunreinigungen
endotoxin, heavy metals, trace metals, tested
mp (Schmelzpunkt)
>300 °C (lit.)
Löslichkeit
H2O: ≥100 mg/mL
Fremdaktivität
cytotoxicity, tested
SMILES String
NCCS(O)(=O)=O
InChI
1S/C2H7NO3S/c3-1-2-7(4,5)6/h1-3H2,(H,4,5,6)
InChIKey
XOAAWQZATWQOTB-UHFFFAOYSA-N
Angaben zum Gen
rat ... Ppm1a(24666)
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Allgemeine Beschreibung
Our SAFC® portfolio of high-quality raw materials for use in biopharmaceutical processing withstands strict quality control procedures plus the documentation and expertise to help our customers meet requirements as defined by the M-Clarity Program.
M-Clarity Program
Our comprehensive portfolio of upstream process chemicals not only provides biopharmaceutical manufacturers with high-quality raw materials for production of classical and novel therapies, but also helps them get to market faster and simplify regulatory challenges. Trust us to deliver supply chain transparency and reliable sourcing around the globe, streamlining your product qualification with best-in-class regulatory support and service.
M-Clarity Program
Our comprehensive portfolio of upstream process chemicals not only provides biopharmaceutical manufacturers with high-quality raw materials for production of classical and novel therapies, but also helps them get to market faster and simplify regulatory challenges. Trust us to deliver supply chain transparency and reliable sourcing around the globe, streamlining your product qualification with best-in-class regulatory support and service.
To request documentation for this product, please contact Customer Support and select ‘Product Documentation′. Please note that access to documentation for this product requires a confidentiality disclosure agreement.
Anwendung
Taurine is a derivative of the sulfur-containing (sulfhydryl) amino acid cysteine. Taurine is one of the few known naturally occurring sulfonic acids. It is a conditionally essential sulfonated amino acid which modulates apoptosis in some cells; functions in many metabolic activities; a product of methionine and cysteine metabolism. It can be used as a cell culture media component for the commercial biomanufacture of therapeutic recombinant proteins and monoclonal antibodies.
Biochem./physiol. Wirkung
Nicht selektiver, endogener Agonist an Glycin-Rezeptoren. Bedingt essentielle sulfonierte Aminosäure, die in manchen Zellen die Apoptose moduliert; spielt eine Rolle in zahlreichen Stoffwechselvorgängen; ist ein Produkt des Methionin- und Cysteinstoffwechsels
Rechtliche Hinweise
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany
Lagerklassenschlüssel
11 - Combustible Solids
WGK
WGK 2
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
Persönliche Schutzausrüstung
dust mask type N95 (US), Eyeshields, Gloves
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Takashi Ito et al.
Journal of molecular and cellular cardiology, 44(5), 927-937 (2008-04-15)
The sulfur-containing beta-amino acid, taurine, is the most abundant free amino acid in cardiac and skeletal muscle. Although its physiological function has not been established, it is thought to play an important role in ion movement, calcium handling, osmoregulation and
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