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Merck

T3397

Sigma-Aldrich

Tylosin solution

solution, suitable for cell culture, BioReagent

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About This Item

CAS-Nummer:
MDL-Nummer:
UNSPSC-Code:
12352207
PubChem Substanz-ID:
NACRES:
NA.76

product name

Tylosin solution, 8 mg/mL in 0.9% NaCl, 0.1 μm filtered, BioReagent, suitable for cell culture

Qualitätsniveau

Sterilität

0.1 μm filtered

Produktlinie

BioReagent

Form

solution

Konzentration

8 mg/mL in 0.9% NaCl

Methode(n)

cell culture | mammalian: suitable

Verunreinigungen

endotoxin, tested

Farbe

colorless to yellow

Wirkungsspektrum von Antibiotika

Gram-positive bacteria
mycoplasma

Wirkungsweise

protein synthesis | interferes

Lagertemp.

2-8°C

SMILES String

O[C@H]([C@@H](O)C(O)=O)C(O)=O.CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O[C@H]3C[C@@](C)(O)[C@@H](O)[C@H](C)O3)[C@@H]([C@H]2O)N(C)C)[C@@H](CC=O)C[C@@H](C)C(=O)\C=C\C(C)=C\[C@@H]1CO[C@@H]4O[C@H](C)[C@@H](O)[C@@H](OC)[C@H]4OC

InChI

1S/C46H77NO17.C4H6O6/c1-13-33-30(22-58-45-42(57-12)41(56-11)37(52)26(5)60-45)18-23(2)14-15-31(49)24(3)19-29(16-17-48)39(25(4)32(50)20-34(51)62-33)64-44-38(53)36(47(9)10)40(27(6)61-44)63-35-21-46(8,55)43(54)28(7)59-35;5-1(3(7)8)2(6)4(9)10/h14-15,17-18,24-30,32-33,35-45,50,52-55H,13,16,19-22H2,1-12H3;1-2,5-6H,(H,7,8)(H,9,10)/b15-14+,23-18+;/t24-,25+,26-,27-,28+,29+,30-,32-,33-,35+,36-,37-,38-,39-,40-,41-,42-,43+,44+,45-,46-;1-,2-/m11/s1

InChIKey

ICVKYYINQHWDLM-KBEWXLTPSA-N

Allgemeine Beschreibung

Chemical structure: macrolide
Tylosin is a macrolide antibiotic, which comprises of a 16-member lactone ring. This solution is recommended for use at 1 mL/L.

Anwendung

Tylosin solution has been used as an antimicrobial agent in antibiotic susceptibility minimal inhibitory concentration(MIC) of E. coli and S. aureus isolates. It has also been used as a component of Dulbecco′s modified Eagle′s (DMEM) medium for self-inactivating lentivirus production and skin fibroblast cultivation.

Biochem./physiol. Wirkung

Tylosin inhibits bacterial protein synthesis by binding to the large subunit 50S. It is effective against Gram-positive bacteria and mycoplasma and is used in veterinary medicine. It has been used to study implant site abscess prevention in cattle and Mycoplasma gallisepticum and Mycoplasma meleagridis infections.

Verpackung

20ML

Angaben zur Herstellung

This product was formulated to contain 8 mg/ml tylosin in 0.9% sodium chloride.

Lagerung und Haltbarkeit

Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and keep upright to prevent leakage.

Sonstige Hinweise

Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage.

Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 2

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


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