Alle Fotos(1)

Wichtige Dokumente

SRP6171

IL-3 human

Name: IL-3 human
Brand: SIGMA

recombinant, expressed in HEK 293 cells, ≥95% (SDS-PAGE)

Synonym(e):

HCGF, MGC79398, Mast cell growth factor (MCGF), Multi-CSF, P-cell stimulation factor

Anmeldenzur Ansicht organisationsspezifischer und vertraglich vereinbarter Preise

Alle Fotos(1)

About This Item

UNSPSC-Code:

12352202

Biologische Quelle

human

Rekombinant

expressed in HEK 293 cells

Assay

≥95% (SDS-PAGE)

Form

lyophilized

Mol-Gew.

17-45 kDa (monomer, glycosylated)

Verpackung

pkg of 10 μg

Methode(n)

cell culture | mammalian: suitable

NCBI-Hinterlegungsnummer

P08700

Versandbedingung

dry ice

Lagertemp.

−70°C

Angaben zum Gen

human ... IL3(3562)

Allgemeine Beschreibung

IL3 is a potent growth promoting cytokine. This cytokine is capable of supporting the proliferation of a broad range of hematopoietic cell types. It stimulates colony formation of megakaryocytes, neutrophils, and macrophages from bone marrow cultures. It is also involved in a variety of cell activities such as cell growth, differentiation and apoptosis. This cytokine has been shown to also possess neurotrophic activity, and it may be associated with neurologic disorders.

Physikalische Form

Lyophilized from a PBS solution.

Angaben zur Herstellung

Centrifuge the vial prior to opening.

Rekonstituierung

Reconstitute in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Hier finden Sie alle aktuellen Versionen:

Analysenzertifikate (COA)

Lot/Batch Number

Leider sind derzeit keine COAs für dieses Produkt online verfügbar.

Wenn Sie Hilfe benötigen, wenden Sie sich bitte an Kundensupport

Besitzen Sie dieses Produkt bereits?

In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Basophils exhibit antibacterial activity through extracellular trap formation.

S Yousefi et al.

Allergy, 70(9), 1184-1188 (2015-06-05)

Basophils are primarily associated with immunomodulatory functions in allergic diseases and parasitic infections. Recently, it has been demonstrated that both activated human and mouse basophils can form extracellular DNA traps (BETs) containing mitochondrial DNA and granule proteins. In this report

Low-dose decitabine promotes megakaryocyte maturation and platelet production in healthy controls and immune thrombocytopenia.

Hai Zhou et al.

Thrombosis and haemostasis, 113(5), 1021-1034 (2015-01-09)

Impaired megakaryocyte maturation and insufficient platelet production have been shown to participate in the pathogenesis of immune thrombocytopenia (ITP). Our previous study demonstrated that low expression of tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) in megakaryocytes contributed to impaired platelet production

Genuine Immunomodulation With dSLIM.

Kerstin Kapp et al.

Molecular therapy. Nucleic acids, 3, e170-e170 (2014-06-25)

Toll-like receptors are sensing modulators of the innate immune system. One member of this protein family, Toll-like receptor (TLR)-9, is increasingly being investigated as therapeutic target for infectious diseases and cancer. Double-Stem Loop ImmunoModulator (dSLIM) is a new TLR-9 agonist

Blockade of type I interferon (IFN) production by retroviral replicating vectors and reduced tumor cell responses to IFN likely contribute to tumor selectivity.

Amy H Lin et al.

Journal of virology, 88(17), 10066-10077 (2014-06-27)

We developed a Moloney mouse leukemia virus (MLV)-based retroviral replicating vector (RRV), Toca 511, which has displayed tumor specificity in resected brain tumor material and blood in clinical trials. Here, we investigated the interaction between Toca 511 and human host

Breast Cancer Cell-Derived GM-CSF Licenses Regulatory Th2 Induction by Plasmacytoid Predendritic Cells in Aggressive Disease Subtypes.

Cristina Ghirelli et al.

Cancer research, 75(14), 2775-2787 (2015-05-16)

Reciprocal interactions between tumor cells and their microenvironment vitally impact tumor progression. In this study, we show that GM-CSF produced by primary breast tumor cells induced the activation of plasmacytoid predendritic cells (pDC), a cell type critical to anti-viral immunity.

Alle zugehörigen Dokumente anzeigen

Unser Team von Wissenschaftlern verfügt über Erfahrung in allen Forschungsbereichen einschließlich Life Science, Materialwissenschaften, chemischer Synthese, Chromatographie, Analytik und vielen mehr..

Setzen Sie sich mit dem technischen Dienst in Verbindung.