SRP6100

GSTM2 human

recombinant, expressed in E. coli, ≥95% (SDS-PAGE)

• Synonym(e): GST4, GSTM, GSTM2-2, GTHMUS, Glutathione S-transferase Mu 2
• UNSPSC-Code: 12352202
• NACRES: NA.32

Eigenschaften

• Biologische Quelle: human
• Rekombinant: expressed in E. coli
• Assay: ≥95% (SDS-PAGE)
• Form: liquid
• Wirksamkeit: <25 units/mg
• Mol-Gew.: 27.9 kDa
• Verpackung: pkg of 100 μg
• NCBI-Hinterlegungsnummer: P28161
• UniProt-Hinterlegungsnummer: P28161
• Versandbedingung: dry ice
• Lagertemp.: −70°C
• Angaben zum Gen: human ... GSTM2(2946)

Beschreibung

Allgemeine Beschreibung

Glutathione S-transferase Mu 2 (GSTM2) belongs to the Glutathione S-Transferase (GST) family of proteins. There are 8 families of GST proteins: alpha, kappa, mu, omega, pi, sigma, theta and zeta, each of which is composed of proteins that have various functions throughout the cell. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are structured in a gene cluster on chromosome 1p13.3 and are proven to be highly polymorphic. These genetic variants can change an individual′s susceptibility to carcinogens and toxins as well as have an effect on the toxicity and efficacy of several drugs.

Physikalische Form

0.5 mg/mL solution in 20 mM Tris HCl (pH 8.0) containing 10% glycerol, 0.1 M NaCl and 1 mM DTT.

Angaben zur Herstellung

Centrifuge the vial prior to opening.

Sonstige Hinweise

MGSSHHHHHH SSGLVPRGSH MPMTLGYWNI RGLAHSIRLL LEYTDSSYEE KKYTMGDAPD YDRSQWLNEK FKLGLDFPNL PYLIDGTHKI TQSNAILRYI ARKHNLCGES EKEQIREDIL ENQFMDSRMQ LAKLCYDPDF EKLKPEYLQA LPEMLKLYSQ FLGKQPWFLG DKITFVDFIA YDVLERNQVF EPSCLDAFPN LKDFISRFEG LEKISAYMKS SRFLPRPVFT KMAVWGNK

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable