SML3599

IMP-1575

≥98% (HPLC)

• Synonym(e): (+)-(R)-IMP-1575, (+)-IMP-1575, (R)-(+)-2-(Isobutylamino)-1-(4-(6-methylpyridin-2-yl)-6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)ethan-1-one, (R)-1-[6,7-Dihydro-4-(6-methyl-2-pyridinyl)thieno[3,2-c]pyridin-5(4H)-yl]-2-[(2-methylpropyl)amino]ethenone, (R)-IMP-1575
• Empirische Formel (Hill-System): C₁₉H₂₅N₃OS
• Molekulargewicht: 343.49
• UNSPSC-Code: 51111800
• UNSPSC-Code: 12352200
• NACRES: NA.21

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥98% (HPLC)
• Form: oil
• Farbe: , Faint yellow to yellow orange
• Lagertemp.: 2-8°C
• SMILES String: CC1=CC=CC([C@@H]2N(CCC3=C2C=CS3)C(CNCC(C)C)=O)=N1
• InChIKey: OVUGAMKQXDOHDJ-LJQANCHMSA-N

Beschreibung

Biochem./physiol. Wirkung

Donor substrate Pal-CoA-competitive hedgehog acyltransferase (HHAT) inhibitor with significantly higher potency than its structure analog RUSKI-201.

IMP-1575 is a donor substrate Pal-CoA-competitive (Ki = 38 nM) hedgehog acyltransferase (HHAT) inhibitor with significantly higher potency than its structure analog RUSKI-201 (IC50 = 0.75 vs. 2.0 μM, respectively, by Acyl-cLIP assay).

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable