SML3581

NVP-ACQ090

≥98% (HPLC)

• Synonym(e): 1-[[(4S,4aS,8aR)-Decahydro-2-[(2S)-3-(6-methoxy-3-pyridinyl)-2-methylpropyl]-4-isoquinolinyl]carbonyl]-4-(3,4-difluorophenyl)-piperazine, ACQ 090, ACQ-090, ACQ090, [(4S,4aS,8aR)-Decahydro-2-[(2S)-3-(6-methoxy-3-pyridinyl)-2-methylpropyl]-4-isoquinolinyl][4-(3,4-difluorophenyl)-1-piperazinyl]methanone, [4-(3,4-Difluoro-phenyl)-piperazine-1-yl]-{(4S,4aS,8aR)-2[(S)-3-(6-methoxy-pyridin-3-yl)-2-methyl-propyl]-decahydroisoquinoline-4-yl}-methanone
• Empirische Formel (Hill-System): C₃₀H₄₀F₂N₄O₂
• CAS-Nummer: 362612-47-3
• Molekulargewicht: 526.66
• UNSPSC-Code: 51111800
• UNSPSC-Code: 12352200
• NACRES: NA.77

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥98% (HPLC)
• Form: powder
• Farbe: white to beige
• Löslichkeit: DMSO: 2 mg/mL, clear
• Lagertemp.: 2-8°C

Beschreibung

Biochem./physiol. Wirkung

NVP-ACQ090 is a non-peptidic, potent and subtype-selective somatostatin (SRIF; somatotropin release-inhibiting factor) receptor (SST3; SSTR3) antagonist (hSST3 pKD = 8.15, hSSTR1/2/4/5 pKD = 5.69/5.34/5.83/5.95). NVP-ACQ090 blocks hSST3 phosphorylation induced by somatostatin-14 (SS-14) in cultures and impaires object recognition in wild-type mice in vivo (50 μg/kg i.p.).

Non-peptidic, potent and subtype-selective somatostatin (SRIF; somatotropin release-inhibiting factor) receptor (SST3; SSTR3) antagonist in vitro and in vivo

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable