SML3409

ATN-224

≥95% (elemental analysis)

• Synonym(e): 2-hydroxy-N,N,N-trimethylethanaminium tetrathiomolybdate, ALXN1840, Bis-Choline-Tetrathiomolybdate, Tiomolibdate Choline, WTX101
• Empirische Formel (Hill-System): C₁₀H₂₈N₂O₂ · MoS₄
• CAS-Nummer: 649749-10-0
• Molekulargewicht: 432.54
• MDL-Nummer: MFCD25976790
• UNSPSC-Code: 12352200
• NACRES: NA.77

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥95% (elemental analysis)
• Form: powder
• Lagerbedingungen: desiccated
• Farbe: , Orange to very dark red
• Löslichkeit: H₂O: ≥0.1 mg/mL, clear
• Lagertemp.: -10 to -25°C
• SMILES String: S=[Mo]([S-])([S-])=S.C[N+](C)(CCO)C.C[N+](C)(CCO)C
• InChI: 1S/2C5H14NO.Mo.4S/c2*1-6(2,3)4-5-7;;;;;/h2*7H,4-5H2,1-3H3;;;;;/q2*+1;;;;2*-1
• InChIKey: NEYVHGQOGHJAAD-UHFFFAOYSA-N

Beschreibung

Biochem./physiol. Wirkung

ATN-224 (Bis-Choline-Tetrathiomolybdate) is an orally available and potent inhibitor of superoxide dismutase 1 (SOD1) that exhibit potent anticancer activities. ATN-224 is a copper chelator that rapidly lowers free coper levels and improve clinical symptoms in Wilson′s disease patients.

Inhibitor of superoxide dismutase 1 (SOD1); Reactive oxygen species (ROS) scavenging blocker

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable