SML3070

PSEM89S Hydrochloride salt

≥98% (HPLC)

• Synonym(e): (S)-2,5-Dimethoxy-N-(quinuclidin-3-yl)benzamide, Hydrochloride salt, N-(3S)-1-Azabicyclo[2.2.2]oct-3-yl-2,5-dimethoxybenzamide Hydrochloride salt, PSEM 89S Hydrochloride salt, PSEM-89S Hydrochloride salt
• Empirische Formel (Hill-System): C₁₆H₂₂N₂O₃ · HCl
• CAS-Nummer: 1221570-55-3
• Molekulargewicht: 326.82
• UNSPSC-Code: 12352200
• NACRES: NA.77

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥98% (HPLC)
• Form: powder
• Lagerbedingungen: desiccated
• Farbe: white to beige
• Löslichkeit: DMSO: 2 mg/mL, clear
• Lagertemp.: 2-8°C
• SMILES String: O=C(N[C@@H]1CN2CCC1CC2)C3=C(C=CC(OC)=C3)OC.Cl

Beschreibung

Biochem./physiol. Wirkung

PSEM89S is a pharmacologically selective effector molecule (PSEM) that acts as a selective agonist in vitro and in vivo for chimeric pharmacologically selective actuator modules (PSAMs) composed of nAChR α7 ligand-binding domain (LBD) with L141F mutation fused to the ion pore domain (IPD) of a ligand-gated ion channel (LGIC), including glycine receptor (PSAML^141F-GlyR & PSAML^141F/Y115F-GlyR). 5-HT3 (PSAML^141F-5-HT3 & PSAML^141F/Y115F-5-HT3) and high-conductance 5-HT3 (PSAML^141F-5-HT3 HC & PSAML^141F/Y115F-5-HT3 HC).

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable