SML2517

Tanshinone II-A sodium sulfonate

≥95%

• Synonym(e): 6,7,8,9,10,11-hexahydro-1,6,6-Trimethyl-10,11-dioxo-phenanthro[1,2-b]furan-2-sulfonic acid sodium salt, Sodium tanshinone IIA sulfonate, Sulfotanshinone sodium II-A, TIIAS
• Empirische Formel (Hill-System): C₁₉H₁₇NaO₆S
• CAS-Nummer: 69659-80-9
• Molekulargewicht: 396.39
• MDL-Nummer: MFCD09028094
• UNSPSC-Code: 12352200
• NACRES: NA.77

Eigenschaften

• Assay: ≥95%
• Form: powder
• Farbe: white to beige
• Löslichkeit: H₂O: 2 mg/mL, clear (warmed)
• Lagertemp.: 2-8°C
• SMILES String: CC1(C)CCCC2=C3C(C(OC(S(=O)(O[Na])=O)=C4C)=C4C(C3=O)=O)=CC=C21
• InChI: 1S/C19H18O6S.Na/c1-9-13-15(20)16(21)14-10-5-4-8-19(2,3)12(10)7-6-11(14)17(13)25-18(9)26(22,23)24;/h6-7H,4-5,8H2,1-3H3,(H,22,23,24);/q;+1/p-1
• InChIKey: AZEZEAABTDXEHR-UHFFFAOYSA-M

Beschreibung

Biochem./physiol. Wirkung

Tanshinone II A sulfonate is a water-soluble derivative of tanshinone II A that exhibits anti-inflammatory properties in rodent models of hepatitis and sepsis. Tanshinone II A sulfonate targets Ca²⁺-activated potassium channels and carboxylesterase 2. Recent studies indicate that tanshinone II A sulfonate but not tanshinone II A acts as potent negative allosteric modulator of the human purinergic receptor P2X7.

anti-inflammatory, potent negative allosteric modulator of the human purinergic receptor P2X7

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable