SML2388

SW157765

≥98% (HPLC)

• Synonym(e): 3-(2-Furanyl)-N-[2-(4-pyridinyl)-5-benzoxazolyl]-2-propenamide
• Empirische Formel (Hill-System): C₁₉H₁₃N₃O₃
• CAS-Nummer: 332063-87-3
• Molekulargewicht: 331.32
• MDL-Nummer: MFCD01539854
• UNSPSC-Code: 12352200
• NACRES: NA.77

Eigenschaften

• Assay: ≥98% (HPLC)
• Form: powder
• Farbe: white to brown
• Löslichkeit: DMSO: 2 mg/mL, clear
• Lagertemp.: 2-8°C
• SMILES String: N(c2cc3nc([o]c3cc2)c4ccncc4)C(=O)\C=C\c1[o]ccc1
• InChI: 1S/C19H13N3O3/c23-18(6-4-15-2-1-11-24-15)21-14-3-5-17-16(12-14)22-19(25-17)13-7-9-20-10-8-13/h1-12H,(H,21,23)/b6-4+
• InChIKey: QSSYRORXXFTVFI-GQCTYLIASA-N

Beschreibung

Biochem./physiol. Wirkung

SW157765 is a selective inhibitor of the non-canonical glucose transporter GLUT8 (SLC2A8), which exhibit potent anticancer activity on KRAS/KEAP1 mutant NSCLC cells that selectively depend on GLUT8 for glucose intake to support serine biosynthesis.

selective inhibitor of the non-canonical glucose transporter GLUT8 (SLC2A8)

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable