SML1198

Terutroban

≥95% (HPLC)

• Synonym(e): (6R)-6-[[(4-Chlorophenyl)sulfonyl]amino]-5,6,7,8-tetrahydro-2-methyl-1-Naphthalenepropanoic acid, (R)-6-[[(4-Chlorophenyl)sulfonyl]amino]-5,6,7,8-tetrahydro-2-methyl-1-Naphthalenepropanoic acid, S18886
• Empirische Formel (Hill-System): C₂₀H₂₂ClNO₄S
• CAS-Nummer: 165538-40-9
• Molekulargewicht: 407.91
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 329825715
• NACRES: NA.77

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥95% (HPLC)
• Form: powder
• Optische Aktivität: [α]/D 25 to 31°, c = 1 in DMSO
• Lagerbedingungen: desiccated
• Farbe: white to beige
• Löslichkeit: DMSO: 10 mg/mL, clear
• Lagertemp.: −20°C
• SMILES String: O=S(N[C@@H]1CC2=CC=C(C)C(CCC(O)=O)=C2CC1)(C3=CC=C(Cl)C=C3)=O
• InChI: 1S/C20H22ClNO4S/c1-13-2-3-14-12-16(6-9-19(14)18(13)10-11-20(23)24)22-27(25,26)17-7-4-15(21)5-8-17/h2-5,7-8,16,22H,6,9-12H2,1H3,(H,23,24)/t16-/m0/s1
• InChIKey: HWEOXFSBSQIWSY-INIZCTEOSA-N

Beschreibung

Biochem./physiol. Wirkung

Terutroban is a highly selective and long-acting thromboxane/prostaglandin endoperoxide receptor (TPr) antagonist. The compound Terutroban blocks thromboxane induced platelet aggregation and vasoconstriction. Terutroban prevents vascular wall proliferation and atherogenesis, increases anti-oxidant enzymes like glutathione peroxidase, and has anti-inflammatory properties.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H315,H319,H335
• P-Sätze: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable