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SML1073

Sigma-Aldrich

BIX

≥98% (HPLC)

Synonym(e):

2-(3,4-Dihydroxyphenyl)-2-oxoethyl ester thiocyanic acid, BiP protein Inducer X

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About This Item

Empirische Formel (Hill-System):
C9H7NO3S
CAS-Nummer:
101714-41-4
Molekulargewicht:
209.22
MDL-Nummer:
MFCD22415334
UNSPSC-Code:
12352200
PubChem Substanz-ID:
329825455
NACRES:
NA.77

Qualitätsniveau

100

Assay

≥98% (HPLC)

Form

powder

Farbe

white to beige

Löslichkeit

DMSO: 20 mg/mL, clear

Lagertemp.

2-8°C

SMILES String

OC1=C(O)C=C(C(CSC#N)=O)C=C1

InChI

1S/C9H7NO3S/c10-5-14-4-9(13)6-1-2-7(11)8(12)3-6/h1-3,11-12H,4H2

InChIKey

SVFLBLCWKKQKDW-UHFFFAOYSA-N

Anwendung

BIX has been used in cell viability assay.

Biochem./physiol. Wirkung

BIX (BiP protein inducer X) induces the expression of the endoplasmic reticulum chaperone protein GRP78 (glucose regulated protein 78, BiP) leading to an attenuation of the unfolded protein response. BIX protects neuronal cells and retinal cells from ER-stress induced cell death.
BIX is an inducer of molecular chaperone GRP78 (BIP, Glucose regulated protein 78).

Sonstige Hinweise

air sensitive

Piktogramme

Exclamation mark
GHS07

Signalwort

Warning

H-Sätze

H317

Gefahreneinstufungen

Skin Sens. 1

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

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Analysenzertifikate (COA)

Lot/Batch Number
074M4616V

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Verwandter Inhalt

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DISCOVER Bioactive Small Molecules for Nitric Oxide & Cell Stress Research

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