SML0864

EMPA

≥98% (HPLC)

• Synonym(e): N-Ethyl-2-[(6-methoxy-3-pyridinyl)[(2-methylphenyl)sulfonyl]amino]-N-(3-pyridinylmethyl)-acetamide
• Empirische Formel (Hill-System): C₂₃H₂₆N₄O₄S
• CAS-Nummer: 680590-49-2
• Molekulargewicht: 454.54
• UNSPSC-Code: 51111800
• NACRES: NA.77

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥98% (HPLC)
• Form: film
• Farbe: white to light brown
• Lagertemp.: −20°C
• SMILES String: [S](=O)(=O)(N(CC(=O)N(CC)Cc3cnccc3)c2cnc(cc2)OC)c1c(cccc1)C
• InChI: 1S/C23H26N4O4S/c1-4-26(16-19-9-7-13-24-14-19)23(28)17-27(20-11-12-22(31-3)25-15-20)32(29,30)21-10-6-5-8-18(21)2/h5-15H,4,16-17H2,1-3H3
• InChIKey: KJPHTXTWFHVJIG-UHFFFAOYSA-N

Beschreibung

Biochem./physiol. Wirkung

EMPA is a potent, selective OX2R antagonist (IC₅₀ = 2.3 nM). EMPA binds reversibly to OX2R and inhibits orexin-a and -b-evoked intracellular calcium flux in cells expressing recombinant OX2R, but not OX1R.

EMPA is a potent, selective OX2R antagonist.

Physikalische Form

This product is solubilized for packaging and then dried down for shipment. It would appear as a lyophilized powder or film on the vial. Solvent should be added directly to the vial to prepare their sample for testing.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H302
• P-Sätze: P264 - P270 - P301 + P312 - P501
• Gefahreneinstufungen: Acute Tox. 4 Oral
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable