SML0617

A-804598

≥98% (HPLC)

• Synonym(e): N-Cyano-N′′-[(1S)-1-phenylethyl]-N′-5-quinolinyl-guanidine
• Empirische Formel (Hill-System): C₁₉H₁₇N₅
• CAS-Nummer: 1125758-85-1
• Molekulargewicht: 315.37
• UNSPSC-Code: 12352200
• NACRES: NA.77

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥98% (HPLC)
• Form: powder
• Farbe: white to beige
• Löslichkeit: DMSO: 10 mg/mL, clear
• Lagertemp.: 2-8°C
• InChI: 1S/C19H17N5/c1-14(15-7-3-2-4-8-15)23-19(22-13-20)24-18-11-5-10-17-16(18)9-6-12-21-17/h2-12,14H,1H3,(H2,22,23,24)/t14-/m0/s1
• InChIKey: PQYCRDPLPKGSME-AWEZNQCLSA-N

Beschreibung

Biochem./physiol. Wirkung

A-804598 is a P2X7 selective, competitive antagonist. In competition assays, the IC₅₀s for human, rat and mouse channels are 11, 10 and 9 nM, respectively.

Leistungsmerkmale und Vorteile

This compound is featured on the P2 Receptors: P2X Ion Channel Family page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Sicherheitshinweise

• Piktogramme: GHS06
• Signalwort: Danger
• H-Sätze: H301
• P-Sätze: P264 - P270 - P301 + P310 - P405 - P501
• Gefahreneinstufungen: Acute Tox. 3 Oral
• Lagerklassenschlüssel: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable